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Sorghum bicolor subsp. drummondii pollen
go.drugbank.com/drugs/DB10966ApprovedSorghum bicolor subsp. drummondii pollen is the pollen of the Sorghum bicolor subsp. drummondii plant. Sorghum bicolor subsp. drummondii pollen is mainly used in allergenic testing.
XAV-19
go.drugbank.com/drugs/DB15895InvestigationalAs of July, 2020, the company is conducting a Phase 2 randomized clinical trial to define dosing safety and efficacy of XAV-19 (NCT04453384). … Xenothera has partnered with LFB, a pharmaceutical company, to develop XAV-19, and with Nantes University Hospital to test the treatment in patients[L16553,L16558].
D-Serine
go.drugbank.com/drugs/DB03929ApprovedInvestigationalWithdrawnA non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
Synonyms: d-SerineVelusetrag
go.drugbank.com/drugs/DB12702InvestigationalVelusetrag was discovered by Theravance through the application of its multivalent drug design in a research program dedicated to finding new treatments for GI motility disorders. … It is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance.
RG2417
go.drugbank.com/drugs/DB05055InvestigationalRG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential … Uridine is synthesized by the mitochondria, the power plant of the human cell responsible for energy metabolism.
TD-2749
go.drugbank.com/drugs/DB05905ExperimentalTD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders … such as chronic constipation, constipation-predominant irritable bowel syndrome (C-IBS), opioid-induced constipation, functional dyspepsia and diabetic gastroparesis.
Categories: Heterocyclic Compounds, 1-RingGSK-923295
go.drugbank.com/drugs/DB06097InvestigationalGSK-923295 is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E (CENP-E), and the third novel drug candidate to arise from Cytokinetics' broad strategic alliance with GlaxoSmithKline … GSK-923295 is the first drug candidate to enter human clinical trials that specifically targets CENP-E and is currently in Phase I human clinical trials being conducted by GSK.
Dehydroascorbic acid
go.drugbank.com/drugs/DB08830ExperimentalDehydroascorbic acid as well as ascorbic acid are both termed Vitamin C, but the latter is the main form found in humans. … Dehydroascorbic acid is made from the oxidation of ascorbic acid. This reaction is reversible, but dehydroascorbic acid can instead undergo irreversible hydrolysis to 2,3-diketogulonic acid.
Synonyms: L-threo-2,3-hexodiulosonic acid, γ-lactone, L-dehydroascorbateCategories: Vitamin C and analoguesLinifanib
go.drugbank.com/drugs/DB06080InvestigationalLinifanib is intended for the treatment of hematologic malignancies and the solid tumors. … Linifanib (ABT-869) is a small molecule vascular endothelial growth factor (VEGF) receptor-based kinase inhibitor that is designed to suppress tumor growth by preventing the formation of new blood vessels
Synonyms: 1-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-3-(2-FLUORO-5-METHYLPHENYL)UREA, UREA, N-(4-(3-AMINO-1H-INDAZOL-4-YL)PHENYL)-N'-(2-FLUORO-5-METHYLPHENYL)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLexacalcitol
go.drugbank.com/drugs/DB03451ExperimentalIt is known to target the vitamin D3 receptor. … Lexacalcitol is a solid. This compound belongs to the vitamin D and derivatives class of chemicals. These are compounds containing a secosteroid backbone, usually secoergostane or secocholestane.
Categories: Vitamin D and Analogues