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Displaying results 5281 - 5290 of 10000 in total
  1. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe ā€¦ [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS.

    Synonyms: gene editing consisting of a guide RNA (gRNA), Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated
  2. Drug

    Desfesoterodine

    go.drugbank.com/drugs/DB15578
    Investigational

    Desfesoterodine is a metabolite of [tolterodine].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: 5-Hydroxymethyltolterodine
  3. Drug

    Cryptotanshinone

    go.drugbank.com/drugs/DB15579
    Experimental

    Synonyms: Tanshinone CCategories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  4. Drug

    Chrysin

    go.drugbank.com/drugs/DB15581
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  5. Drug

    Fluazuron

    go.drugbank.com/drugs/DB15583
    Experimental

    Fluazuron is a benzoyl phenylurea compound.

  6. Drug

    Patulin

    go.drugbank.com/drugs/DB15586
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  7. Drug

    Antimony potassium tartrate

    go.drugbank.com/drugs/DB15587
    Experimental

    Antimony potassium tartrate is a schistosomicide possibly useful against other parasites. It has irritant emetic properties and may cause lethal cardiac toxicity among other adverse effects.

    Synonyms: Potassium antimonyl D-tartrate
  8. Drug

    Golodirsen

    go.drugbank.com/drugs/DB15593
    ApprovedInvestigational

    Golodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). ā€¦ [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets a different genetic mutation.

    Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  9. Drug

    Brilliant blue G

    go.drugbank.com/drugs/DB15594
    Approved

    Brilliant blue G, like its name, imparts a vibrant blue color, facilitating identification of the ILM. It was approved by the FDA for ophthalmic use on December 20, 2019.[L10830] ā€¦ Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Brilliant blue G, Coomassie Brilliant Blue G
  10. Drug

    Ebola Zaire vaccine (live, attenuated)

    go.drugbank.com/drugs/DB15595
    ApprovedInvestigational

    [L10866] In 2014, Merck Inc. signed a licensing agreement with NewLink for further development and marketing. ā€¦ [L10854] Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease.

    Synonyms: Ebola Zaire Vaccine (rVSVāˆ†G-ZEBOV-GP, live), EBOLA ZAƏRE VACCINE (rVSV [DELTA] G-ZEBOV-GP, LIVE)