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Displaying results 521 - 530 of 6949 in total
  1. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    It was developed by Genentech as a drug for the treatment of cancers … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer
  2. Drug

    Methylprednisolone

    go.drugbank.com/drugs/DB00959
    ApprovedInvestigationalVet approved

    Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s. Methylprednisolone was granted FDA approval on 24 October 1957. In the outbre...

    Mixtures: Methylprednisolone Sodium Succinate for Injection, USP, Methylprednisolone Sodium Succinate for Injection, USPCategories: Corticosteroids for Systemic Use, Anti-Acne Preparations for Topical Use
  3. Drug

    Colistin

    go.drugbank.com/drugs/DB00803
    ApprovedInvestigational

    Cyclic polypeptide antibiotic from Bacillus colistinus. It is composed of Polymyxins E1 and E2 (or Colistins A, B, and C) which act as detergents on cell membranes. Colistin is less toxic than Polymyxin B, but otherwise similar; the meth...

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Cofacoli Solution 2MIU/ml Solution for Oral use
  4. Drug

    Ozekibart

    go.drugbank.com/drugs/DB18675
    Investigational

    Ozekibart is a tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5). It is being investigated for the treatment of chondrosarcoma.

    Synonyms: Immunoglobulin, anti-(human death receptor 5) (human-Lama glama clone IF5 single-domain VHH fragment) fusion protein with peptide linker (GGS)2 fusion protein with immunoglobulin anti-(human death receptor, Tetravalent recombinant humanized IgG1 agonist antibody targeting the human TRAIL death receptor 5 (DR5).
  5. Drug

    Dipyridamole

    go.drugbank.com/drugs/DB00975
    ApprovedInvestigational

    A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 199...

    Products: Dipyridamole for Injection
  6. Drug

    Kaolin

    go.drugbank.com/drugs/DB01575
    Approved

    Kaolin is a layered silicate mineral. Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics. Until the early 1990s it was ...

    Products: Druide Biolove for Diaper Rash
  7. Drug

    Midazolam

    go.drugbank.com/drugs/DB00683
    ApprovedIllicitInvestigational

    [F2977] This drug was initially approved by the US FDA in 1985, and has been approved for various indications since. … [L45098] In late 2018, the intramuscular preparation was approved by the FDA for the treatment of status epilepticus in adults.

    Products: MIDAZOLAM-BAXTER SOLUTION FOR INJECTION 1 MG/ML, MIDAZOLAM-BAXTER SOLUTION FOR INJECTION 5 MG/ML
  8. Drug

    AD-114

    go.drugbank.com/drugs/DB18285
    Experimental

    Synonyms: Human single domain antibody-like protein inhibitor of the chemokine receptor type 4
  9. Drug

    Moxifloxacin

    go.drugbank.com/drugs/DB00218
    ApprovedInvestigational

    Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Iventi 400mg/250ml solution for Infusion, AVELOX SOLUTION FOR INFUSION 400 mg/250 ml
  10. Drug

    Budesonide

    go.drugbank.com/drugs/DB01222
    ApprovedInvestigational

    Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. Budesonide was granted FDA approval o...

    Mixtures: SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 80/4.5 mcg/actuation, SYMBICORT RAPIHALER SUSPENSION FOR INHALATION 160/4.5 mcg/actuationCategories: Corticosteroids for Systemic Use, Corticosteroids for inhalation use