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Polymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B has a narrow therapeutic index and so its use is limited and unlikely to be used first line[A176429]. … Polymyxin B was discovered in the 1940s[A176429]. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes[A176426].
Mixtures: Water-Jel 3-in-1 Antibiotic, Zee 3-in-One First Aid AntibioticProducts: POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 10 FLAKON, POLİX 500000 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ (POLİMİSİN), 1 FLAKONIodine
go.drugbank.com/drugs/DB05382ApprovedInvestigationalAdditionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159] … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds.
Mixtures: Multi II IV Vi Tab, Multipack IISynonyms: I2Fosaprepitant
go.drugbank.com/drugs/DB06717ApprovedInvestigationalIt aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. … Fosaprepitant is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant.
Products: Emend IV, EMEND IVTestosterone
go.drugbank.com/drugs/DB00624ApprovedInvestigational[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.[A186943] … Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.
International brands: Testaqua IMProducts: Androgel 25 mg transdermales Gel im Beutel, Androgel 50 mg transdermales Gel im BeutelTopotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: Topoisomerase I InhibitorsProducts: TOPOXIN 4 MG IV INF.ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, HYCAMTIN IV LİYOFİLİZE TOZ İÇEREN ENJEKTABL FLAKON, 1 ADETNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33724] Naloxone is indicated for the rapid reversal of these symptoms of central nervous system depression in opioid overdose. … [L33729,L33739] Naloxone IM injections are commonly available in the form of "kits", which is ideal for making overdose treatment accessible and readily available for administration by minimally trained
Mixtures: VALORON N, VALORON NSynonyms: 1-N-Allyl-14-hydroxynordihydromorphinoneTubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216028] It was first isolated by Harold King in 1935 and was used clinically to induce neuromuscular blockade during surgeries, particularly those involving the abdomen. … [A216048] Safer and more pharmacokinetically favorable non-depolarizing neuromuscular blockers, such as [rocuronium], have largely replaced the use of tubocurarine in the clinical setting.[A216048]
Products: Tubocurarine Chloride Inj 3mg/ml, Tubocurarine Chloride Inj 3mg/ml USPEnflurane
go.drugbank.com/drugs/DB00228ApprovedVet approvedWithdrawnIn addition, it is known to cause increased cardio depressant effects when compared to other inhaled anesthetics.[A202022] … Enflurane is a halogenated inhalational anesthetic initially approved by the FDA in 1972. Since this date, it has been withdrawn from the US market.
Products: Ethrane Liq Inh, Ethrane Liquid InhKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Products: Toradol Im, Toronova II SUIKTicarcillin
go.drugbank.com/drugs/DB01607ApprovedVet approvedWithdrawnAn antibiotic derived from penicillin similar to carbenicillin in action.
Products: Ticar Inj Pws 1gm/vial, Ticar Inj Pws 3gm/vial