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Suplatast
go.drugbank.com/drugs/DB19138InvestigationalSuplatast is under investigation in clinical trial NCT05983471 (Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)).
KT-A261
go.drugbank.com/drugs/DB19317ExperimentalKT-A261 is an adeno-associated viral vector serotype 2 (AAV2) encoded to express adalimumab. It is being investigated for the treatment of noninfectious uveitis.
Litoxetine
go.drugbank.com/drugs/DB15038InvestigationalLitoxetine is under investigation in clinical trial NCT03397771 (DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence).
Plosaracetam
go.drugbank.com/drugs/DB21594InvestigationalThe usage of the INN stem '-racetam' in the name indicates that Plosaracetam is a piracetam type amide type nootrope agent. … Plosaracetam is under investigation in clinical trial NCT05199142 (A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive
PSN9301
go.drugbank.com/drugs/DB05001ExperimentalPSN9301 is an oral small molecule inhibitor of Dipeptidyl Peptidase IV (DP-IV), being developed for the treatment of type 2 diabetes. … PSN9301 has a very rapid onset and a relatively short duration of action, and available pre-clinical and clinical data indicate that it may be an ideal product candidate for meal-related dosing.
RGX-501
go.drugbank.com/drugs/DB17639InvestigationalRGX-501 is an adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human low-density lipoprotein receptor (LDLR) gene to liver cells. … It is being investigated for the treatment of homozygous familial hypercholesterolemia.[L46696]
Brifentanil
go.drugbank.com/drugs/DB09172ExperimentalIllicitThe effects of brifentanil are very similar to those of alfentanil, with strong but short lasting analgesia and sedation, and particularly notable itching and respiratory depression. … This drug is classified as an opioid analgesic and was developed in the early 1990s.
Ladostigil
go.drugbank.com/drugs/DB16213InvestigationalLadostigil is under investigation in clinical trial NCT01429623 (A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment).
Synonyms: Tv-3326 free baseAstegolimab
go.drugbank.com/drugs/DB16386InvestigationalAstegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia).
Indoprofen
go.drugbank.com/drugs/DB08951ApprovedWithdrawnFollowing reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide.