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Displaying results 5301 - 5310 of 10000 in total
  1. Drug

    Eritoran

    go.drugbank.com/drugs/DB04933
    Investigational

    Eritoran is a structural analogue of the lipid A portion of lipopolysaccharide (LPS). It is being developed by Eisai Research Institute of Boston for the treatment of severe sepsis.

  2. Drug

    Tezosentan

    go.drugbank.com/drugs/DB06558
    Investigational

    Tezosentan is an intravenous endothelin receptor A/B antagonist. … Tezosentan was initially developed for vasodilation in patients with acute heart failure but studies have shown that it does not assist in the treatment of dyspnea or prevent cardiovascular events.

  3. Drug

    2-Methoxyestradiol

    go.drugbank.com/drugs/DB02342
    Investigational

    2-Methoxyestradiol (2ME2) is a drug that prevents the formation of new blood vessels that tumors need in order to grow (angiogenesis). … It has undergone Phase 1 clinical trials against breast cancers and preclinical studies suggest that 2ME2 could also be effective against inflammatory diseases such as rheumatoid arthritis.

  4. Drug

    Elm

    go.drugbank.com/drugs/DB14258
    Approved

    Elm is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: Nin Jiom Pei Pa Koa
  5. Drug

    Wormwood

    go.drugbank.com/drugs/DB14291
    Approved

    Wormwood is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Artemisia Absinthium L.
  6. Drug

    Pentosan polysulfate

    go.drugbank.com/drugs/DB00686
    ApprovedInvestigational

    Pentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.

    Synonyms: -D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULFATE, -D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULPHATE
  7. Drug

    EGS21

    go.drugbank.com/drugs/DB05056
    Experimental

    EGS21(TM) is a beta-D-glucosylceramide (GC) compound. It is a potential therapeutic for treating immune mediated disorders. … GC is a glycolipid that has been shown by Enzo scientists and collaborators to act as an anti-inflammatory agent in animal model systems, and therefore is being evaluated as an important candidate

  8. Drug

    CERE-120

    go.drugbank.com/drugs/DB05637
    Investigational

    It was under investigation in clinical trials for the treatment of Parkinson's Disease. … CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor.

  9. Drug

    LIC-477

    go.drugbank.com/drugs/DB05363
    Experimental

    LIC-477is indicated to be suitable for the treatment of psychosomatic disturbances, epilepsy, trigeminal neuralgia and cerebral spasticity.

  10. Drug

    Didesmethylrocaglamide

    go.drugbank.com/drugs/DB15496
    Experimental

    Didesmethylrocaglamide is a naturally-occurring derivative of [rocaglamide] and belongs to a class of anti-cancer phytochemicals referred to as "rocaglamides" derived from plants of the genus _Aglaia_. … [A186760] While traditionally used for their insecticidal benefits,[A186796] this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of various leukemias, lymphomas