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NGX267
go.drugbank.com/drugs/DB05152InvestigationalIt is developed for the treatment of Alzheimer’s disease and has shown the potential to both reduce symptoms and slow disease progression.
TC-5231
go.drugbank.com/drugs/DB05333ExperimentalTC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine.
RESP301
go.drugbank.com/drugs/DB16497InvestigationalAdditionally, RESP301 was investigated in a withdrawn trial (NCT04842331) for preventing viral exposure and transmission of COVID-19 and in a not yet recruiting trial (NCT04386070) for preventing pulmonary
Zosuquidar
go.drugbank.com/drugs/DB06191InvestigationalIt is now in "Phase 3" of clinical tests in the United States. Its action mechanism consists of the inhibition of P-glycoproteins; other drugs with this mechanism include tariquidar and laniquidar.
Atrazine
go.drugbank.com/drugs/DB07392ExperimentalInhalation hazard is low and there are no apparent skin manifestations or other toxicity in humans.
Cloxazolam
go.drugbank.com/drugs/DB01553ExperimentalCloxazolam is a benzodiazepine with anxiolytic, sedative/hypnotic, muscle relaxant, and antiepileptic effects. It is marketed in the Argentina, Australia, Portugal, Belgium, Switzerland, Luxembourg, Germany, Taiwan and Japan -- mainly fo...
AG0301-COVID19
go.drugbank.com/drugs/DB15856InvestigationalAG0301-COVID19 is a vaccine candidate developed by AnGes Inc. and Osaka University. … On September 8, 2020 AnGes announced collaboration with Brickell Biotech, Inc. following completion of Phase 1/2 clinical studies (NCT04463472).
Dichlorvos
go.drugbank.com/drugs/DB11397ExperimentalVet approvedThe compound has been available on the market since 1961 and its use is a controversial topic due to environmental and health concerns. … Dichlorvos is found in urban waterways and its toxicity may impact humans, leading to poisoning, neurotoxicity, and cancer.
Caroxazone
go.drugbank.com/drugs/DB09254ApprovedWithdrawnCaroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents a five-fold preference for the MAO-B subtype.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePF-07799933
go.drugbank.com/drugs/DB17489InvestigationalPF-07799933 is a BRAF class 2 inhibitor developed by Pfizer.