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Branaplam
go.drugbank.com/drugs/DB14918InvestigationalBranaplam is under investigation in clinical trial NCT02268552 (An Open Label Study of LMI070 (Branaplam) in Type 1 Spinal Muscular Atrophy (SMA)).
TPX-4589
go.drugbank.com/drugs/DB18604InvestigationalTPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Telapristone acetate
go.drugbank.com/drugs/DB05253InvestigationalTelapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
IRX-2
go.drugbank.com/drugs/DB05643InvestigationalIt is being investigated to promote or enhance an anti-cancer immune response.
Dirlotapide
go.drugbank.com/drugs/DB11399InvestigationalVet approvedIt is marketed by Pfizer and Zoetis under the brand name, _Slentrol_, and is not intended for human use.
Metampicillin
go.drugbank.com/drugs/DB13836ExperimentalMetampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin.
VA-MENGOC-BC®
go.drugbank.com/drugs/DB15800ExperimentalVA-MENGOC-BC is a meningococcal B and C vaccine and an outer membrane vesicle (OMV)-based vaccine. … Novel antigens such as γ-glutamyltranspeptidase, exopolyphosphatase, and a cell-binding factor protein were also identified with administration of this vaccine by a study.
Medical Cannabis
go.drugbank.com/drugs/DB14009Investigationalstores, blocks low-voltage-activated (T-type) Ca2 channels, stimulates activity of the inhibitory glycine-receptor, and inhibits activity of fatty amide hydrolase (FAAH) [A31555, A31574]. … antagonizes alpha-1 adrenergic and µ-opioid receptors, inhibits synaptosomal uptake of noradrenaline, dopamine, serotonin and gaminobutyric acid and cellular uptake of anandamide, acts on mitochondria Ca2
Pamidronic acid
go.drugbank.com/drugs/DB00282ApprovedInvestigationalPamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less comm...
Calcium threonate
go.drugbank.com/drugs/DB11168ApprovedWithdrawnL-threonate is an active metabolite of vitamin C that mediates a stimulatory action on vitamin C uptake [A27266].