Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary... It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis.
- Mechanism
- Curator reviewed · 3 references
Once dissociated to calcium and L-theronic acid, L-threonic acid exhibits significant stimulatory action on vitamin C uptake and prolongs the retention of vitamin C in human T-lymphoma cells. Vitamin C is a marker for osteoblast formation and has been shown to stimulate procollagen and enhance collagen synthesis. Via stimulation of vitamin C uptake, L-threonic acid acts as a metabolite that influences the mineralization process.
- Primary indication
- No approved therapeutic indications.Curator reviewed
- Formula / weight
- C8H14CaO10 · 310.268 g/mol (avg)
- Also known as
- Calcium L-threonate · Threonine, calcium salt
Resolves to
ZJXGOFZGZFVRHK-BALCVSAKSA-LSMILES[Ca++].OC[C@H](O)[C@@H](O)C([O-])=O.OC[C@H](O)[C@@H](O)C([O-])=OWhat you can answer from here — as of April 02, 2025
Which companies are running trials of Calcium threonate, in which indications and phases, and which of those programs are still active?
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