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Displaying results 5321 - 5330 of 10000 in total
  1. Drug

    HCV-086

    go.drugbank.com/drugs/DB05884
    Experimental

    HCV-086 is a small molecule antiviral designed to block an enzyme required for the replication of the hepatitis C virus.

  2. Drug

    Zalutumumab

    go.drugbank.com/drugs/DB12202
    Investigational

    Zalutumumab is a fully human IgG1 monoclonal antibody designed to bind with selectivity to the epidermal growth factor receptor (EGFR). … Zalutumumab has been investigated for the treatment of Squamous Cell Cancer and Head and Neck Cancer.

  3. Drug

    Placental Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15730
    Investigational

    The placenta serves many purposes, with one of the many being a bank of mesenchymal stem cells (MSCs). … It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells.

  4. Drug

    Tiapride

    go.drugbank.com/drugs/DB13025
    Investigational

    Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.

    Products: TIADAL 100 MG/2 ML AMPUL, 12 ADET
  5. Drug

    Amitraz

    go.drugbank.com/drugs/DB11373
    ExperimentalVet approved

    Amitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. … Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis

    Synonyms: N,N'-(methyliminodimethylidyne)bis-2,4-xylidine, 1,5-di(2,4-dimethylphenyl)-3-methyl-1,3,5-triazapenta-1,4-dieneCategories: Adrenergic alpha-2 Receptor Agonists, Compounds used in a research, industrial, or household setting
  6. Drug

    Fluindione

    go.drugbank.com/drugs/DB13136
    ApprovedWithdrawn

    Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior. … Fluindione has been investigated for the treatment of Blood Coagulation Disorders.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Vitamin K Antagonists
  7. Drug

    L523S

    go.drugbank.com/drugs/DB06498
    Investigational

    According to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) … [A175909] It has been investigated as a lung cancer vaccine.

  8. Drug

    Moxestrol

    go.drugbank.com/drugs/DB13418
    Experimental

    Categories: Sex Hormones and Modulators of the Genital System
  9. Drug

    NUC B1000

    go.drugbank.com/drugs/DB05242
    Experimental

    [F3910] eiRNA is an approach to RNAi therapeutics, whereby a plasmid DNA coding for desired dsRNA is delivered to diseased cells enabling the cells to carry out dsRNA production internally thereby invoking … the RNAi response against a targeted disease causing gene.

  10. Drug

    XL019

    go.drugbank.com/drugs/DB05243
    Investigational

    XL019 is a selective inhibitor of the cytoplasmic tyrosine kinase JAK2. An IND for XL019 was filed by Exelixis in May 2007.