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mRNA-3927
go.drugbank.com/drugs/DB17669InvestigationalmRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid … Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.[L45998]
Molidustat
go.drugbank.com/drugs/DB15642InvestigationalMolidustat is under investigation in clinical trial NCT03350321 (A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects).
Acasunlimab
go.drugbank.com/drugs/DB18932InvestigationalAcasunlimab is under investigation in clinical trial NCT06046274 (GEN1046 in Combination With Anticancer Agents for the Treatment of Advanced Endometrial Cancer).
Bevonescein
go.drugbank.com/drugs/DB19021InvestigationalBevonescein is under investigation in clinical trial NCT06227585 (Feasibility Study- REVEAL 475 for Bevonescein-assisted Nerve Visualization in Head & Neck Surgery).
Lazuvapagon
go.drugbank.com/drugs/DB19046InvestigationalLazuvapagon is under investigation in clinical trial NCT03116191 (Trial of SK-1404 for Nocturia Due to Nocturnal Polyuria in Japanese Subjects).
Synonyms: (4s)-n-((2s)-1-hydroxypropan-2-yl)-methyl-1-(2-methyl-4-(3-methyl-1h-pyrazol-1-yl)benzoyl)-2,3,4,5-tetrahydro-1h-1-benzazepine-4-carboxamide, 1h-1-benzazepine-4-carboxamide, 2,3,4,5-tetrahydro-n-((1s)-2-hydroxy-1-methylethyl)-4-methyl-1-(2-methyl-4-(3-methyl-1h-pyrazol-1-yl)benzoyl)-, (4s)-TD-2749
go.drugbank.com/drugs/DB05905ExperimentalTD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders
UCB7362
go.drugbank.com/drugs/DB17096Experimental[A254232] UCB7362 is estimated to achieve a significant reduction in asexual blood-stage parasites. … UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria.
CRx-119
go.drugbank.com/drugs/DB05688ExperimentalCRx-119 is a novel synergistic combination drug candidate discovered using the CombinatoRx combination High Throughput Screening (cHTS(TM)) technology with potential therapeutic use in a broad range of … CRx-119 is a combination of a low dose of the steroid prednisolone, 3mg, and amoxapine.
Asunercept
go.drugbank.com/drugs/DB15160InvestigationalAsunercept is under investigation in clinical trial NCT02853565 (A Study of CAN008 for Newly Diagnosed Glioblastoma Multiforme).
PARPI F-18
go.drugbank.com/drugs/DB18657ExperimentalPARPI F-18 is a diagnostic agent under investigation for use in the management of glioblastoma multiforme.