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Ponesimod
go.drugbank.com/drugs/DB12016ApprovedInvestigational[A232079,L32709] Ponesimod was developed out of a need for a more selective modulator of sphingosine 1-phosphate receptor 1 than [fingolimod]. … [A232079] Fingolimod's activity at sphingosine 1-phosphate receptor 3 was suspected to be responsible for a portion of it's adverse effects, and so more selective modulators were developed.
Remibrutinib
go.drugbank.com/drugs/DB16852ApprovedInvestigationalRemibrutinib is a selective Bruton's tyrosine kinase inhibitor. The FDA approved remibrutinib on September 30, 2025 as the only oral, targeted treatment for chronic spontaneous urticaria. … [L54101] Bruton's tyrosine kinase plays a role in B cell receptor and Fc receptor signalling, releasing histamine and pro-inflammatory mediators.
Darbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: ARANESP 20UG FS MIT ANS, ARANESP 100UG FS MIT ANSZibrofusidic acid
go.drugbank.com/drugs/DB20799InvestigationalZibrofusidic acid has a monoisotopic molecular weight of 594.26 Da. … Zibrofusidic acid is a small molecule drug.
Evixapodlin
go.drugbank.com/drugs/DB21520InvestigationalEvixapodlin has a monoisotopic molecular weight of 690.22 Da. … Evixapodlin is a small molecule drug.
Abarelix
go.drugbank.com/drugs/DB00106ApprovedWithdrawnIt is marketed by Praecis Pharmaceuticals as Plenaxis. Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.
Metharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnMetharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Vevorisertib
go.drugbank.com/drugs/DB21481InvestigationalVevorisertib has a monoisotopic molecular weight of 586.32 Da. … Vevorisertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Vevorisertib is a serine/threonine kinase inhibitor.
Picafibrate
go.drugbank.com/drugs/DB19574ExperimentalPicafibrate has a monoisotopic molecular weight of 362.1 Da. … Picafibrate is a small molecule drug.
Tiafibrate
go.drugbank.com/drugs/DB19874ExperimentalTiafibrate has a monoisotopic molecular weight of 686.23 Da. … Tiafibrate is a small molecule drug.