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Displaying results 531 - 540 of 10000 in total
  1. Drug

    4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose

    go.drugbank.com/drugs/DB03495
    Experimental

    Synonyms: 4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose
  2. Drug

    H3B-8800

    go.drugbank.com/drugs/DB14017
    Investigational

    H3B-8800 is a novel spliceosome inhibitor developed by H3 Biomedicine [L2551]. … H3B-8800 was granted orphan drug status by the FDA in August 2017 and is in clinical trials for the treatment of acute myelogenous leukemia and chronic myelomonocytic leukemia [L2551].

    Synonyms: (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(2-pyridinyl)-2,4-heptadien-2-yl]oxacyclododec-4-en-6-yl 4-methyl-1-piperazinecarboxylate, (2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-Dimethyl-12-Oxo-2-[(2E,4E,6R)-6-(Pyridin-2-Yl)Hepta-2,4-Dien-2-Yl]Oxacyclododec-4-En-6-Yl 4-Methylpiperazine-1-CarboxylateCategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide

    go.drugbank.com/drugs/DB04002
    Experimental

    Synonyms: 4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide
  4. Drug

    POT-4

    go.drugbank.com/drugs/DB06056
    Investigational

    POT-4 is a peptide that specifically inhibits complement activation and is initially being developed for the treatment of age-related macular degeneration (AMD). … The investigational drug was under investigation in clinical trial NCT00473928 (Safety of Intravitreal POT-4 Therapy for Patients With Neovascular Age-Related Macular Degeneration (AMD) (ASaP)).

  5. Drug

    4-dimethylaminophenol

    go.drugbank.com/drugs/DB13549
    Experimental

    Synonyms: 4-dimethylaminophenolSalts: 4-dimethylaminophenol hydrochloride
  6. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396]. … In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626].

    Synonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastineCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index
  7. Drug

    4-Methylcoumarin

    go.drugbank.com/drugs/DB08785
    Experimental

    Synonyms: 4-Methyl-2H-1-benzopyran-2-one
  8. Drug

    4'-Hydroxyflavanone

    go.drugbank.com/drugs/DB04429
    Experimental

    Synonyms: 4'-HydroxyflavanoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  9. Drug

    4-Deoxylactose

    go.drugbank.com/drugs/DB02065
    Experimental

    Synonyms: 4-Deoxylactose
  10. Drug

    4-Hydroxyphenylglycine

    go.drugbank.com/drugs/DB02601
    Experimental

    Synonyms: (RS)-2-(4-hydroxyphenyl)glycine, 4-HydroxyphenylglycineCategories: Carnitine O-Palmitoyltransferase, antagonists & inhibitors