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Displaying results 5391 - 5400 of 7181 in total
  1. Drug

    Pirlimycin

    go.drugbank.com/drugs/DB11537
    ExperimentalVet approved

    Pirlimycin hydrochloride is an antibiotic belonging to the _lincosamide_ class. Often marketed as _Pirsue_, this drug is used to treat mastitis in cattle.

  2. Drug

    BMS-817399

    go.drugbank.com/drugs/DB14941
    Investigational

    BMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).

  3. Target

    Immunoglobulin kappa variable 1D-33

    go.drugbank.com/bio_entities/BE0004164
    TargetHumans

    The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation

    Synonyms: Ig kappa chain V-I region WAT
  4. Drug

    INO-4800

    go.drugbank.com/drugs/DB15693
    Investigational

    Furthermore, the antibodies produced were capable of inhibiting the binding of SARS-CoV-2 to the ACE2 receptor, which is thought to be critical for host cell entry. … [A214475, A214478] Follow up studies in both BALB/c mice and Hartley guinea pigs demonstrated the ability of INO-4800 to induce both humoral and T cell-mediated immunity against SARS-CoV-2, including in

  5. Drug

    Calcitonin porcine

    go.drugbank.com/drugs/DB13189
    Experimental

    Human calcitonin is available only in very small quantities but has been used in some studies. The first commercially available preparation in Britain was porcine calcitonin (brand name Calcitare). … Calcitonin is a polypeptide hormone secreted by the parafollicular cells of the thyroid gland in mammals. It inhibits bone resorption and lowers both serum and urinary calcium concentrations.

  6. Drug

    Rocatinlimab

    go.drugbank.com/drugs/DB18809
    Investigational

    In clinical trials, it has shown significant efficacy and safety compared to a placebo. … Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis.

  7. Drug

    OAV201

    go.drugbank.com/drugs/DB17842
    Experimental

    It was first developed by Novartis and investigated for the treatment of Rett syndrome, but further investigation in clinical trials was halted.[L46661]

  8. Drug

    Prezatide copper

    go.drugbank.com/drugs/DB14683
    Investigational

    It is known to aid wound healing and its potential applications in chronic obstructive pulmonary disease and metastatic colon cancer are currently being investigated.

  9. Drug

    Amaranthus retroflexus pollen

    go.drugbank.com/drugs/DB10381
    Approved

    Amaranthus retroflexus pollen is the pollen of the Amaranthus retroflexus plant. Amaranthus retroflexus pollen is mainly used in allergenic testing.

    Mixtures: Number Two Weed Mixture
  10. Drug

    AN2898

    go.drugbank.com/drugs/DB16039
    Investigational

    AN2898 is under investigation in clinical trial NCT01301508 (Efficacy and Safety of AN2898 and AN2728 Topical Ointments to Treat Mild-to-moderate Atopic Dermatitis).