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Displaying results 5411 - 5420 of 10000 in total
  1. Drug

    Dithioerythritol

    go.drugbank.com/drugs/DB01692
    Experimental

    A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl

    Synonyms: DTE
  2. Drug

    LX201

    go.drugbank.com/drugs/DB04943
    Investigational

    LX201 is a silicone matrix ocular implant that provides sustained release of cyclosporine A (CsA) locally to the eye over the course of one year. … LX201 is implanted subconjunctivally (beneath the transparent membrane covering the white of the eye) in a minimally invasive procedure.

  3. Drug

    PF-06751979

    go.drugbank.com/drugs/DB15105
    Investigational

    PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).

  4. Drug

    Altretamine

    go.drugbank.com/drugs/DB00488
    ApprovedWithdrawn

    An alkylating agent proposed as an antineoplastic. It also acts as a chemosterilant for male houseflies and other insects.

  5. Drug

    3-Fluoro-L-tyrosine

    go.drugbank.com/drugs/DB04436
    Experimental

    This compound belongs to the phenylpropanoic acids. … These are compounds whose structure contain a benzene ring conjugated to a propanoic acid. 3-Fluoro-L-tyrosine targets the protein superoxide dismutase [mn], mitochondrial.

  6. Drug

    Thrombomodulin Alfa

    go.drugbank.com/drugs/DB05777
    Approved

    It is a human protein with both thrombin inhibiting and protein C stimulating activities, for the potential treatment of thromboembolism and blood clotting disorders, such as disseminated intravascular

  7. Drug

    Amitraz

    go.drugbank.com/drugs/DB11373
    ExperimentalVet approved

    Its insecticide effect is due to its agonistic activity in the alpha-adrenergic system, its interaction with the octopamine receptors in the central nervous system and its driven inhibition of the synthesis … All the abovementioned effects are translated into the overexcitation, paralysis, and death in insects.

    Categories: Adrenergic alpha-2 Receptor Agonists
  8. Drug

    TEL540-548

    go.drugbank.com/drugs/DB17461
    Investigational

    TEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT).

  9. Drug

    Uridine monophosphate

    go.drugbank.com/drugs/DB03685
    Investigational

    A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.

  10. Drug

    MEM 1414

    go.drugbank.com/drugs/DB05888
    Experimental

    It appears to work in the area of the brain where new memories are formed. … MEM 1414 is a PDE4 inhibitor that is being evaluated for the treatment of Alzheimer’s disease. This drug candidate has completed Phase 1 clinical trials.