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Displaying results 5481 - 5490 of 5498 in total
  1. Drug

    Erfonrilimab

    go.drugbank.com/drugs/DB17446
    Investigational

    Erfonrilimab is a bispecific monoclonal antibody directed against both the programmed cell death-1 ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA4).

  2. Drug

    UCART22

    go.drugbank.com/drugs/DB17466
    Investigational

    UCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.

    Synonyms: Allogeneic gene-edited CAR T cells UCART22, Allogeneic TALEN gene-edited CAR T-Cells UCART22
  3. Drug

    RO7296682

    go.drugbank.com/drugs/DB17531
    Investigational

    RO7296682 is a monoclonal antibody against CD25 (IL-2R alpha) expressed on tumour-infiltrating regulatory T (T<sub>reg</sub>) cells.

  4. Drug

    NKTT-120

    go.drugbank.com/drugs/DB17730
    Investigational

    NKTT-120 is a recombinant humanized IgG1k monoclonal antibody to human invariant T cell receptor (iTCR).

  5. Drug

    Cerdulatinib

    go.drugbank.com/drugs/DB15499
    Investigational

    Cerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).

  6. Drug

    Tolboxane

    go.drugbank.com/drugs/DB19778
    Experimental

    The usage of the INN stem '-oxan(e)' in the name indicates that Tolboxane is a benzodioxane derivative. Tolboxane has a monoisotopic molecular weight of 232.16 Da.

  7. Drug

    CS1 CAR-T

    go.drugbank.com/drugs/DB33915
    Experimental

    CS1 CAR-T is a biologic drug. CS1 CAR-T is under investigation in clinical trial NCT07809594 (CS1-Targeted CAR-T Cells for Relapsed/Refractory Multiple Myeloma).

    Synonyms: CS1 CAR-T
  8. Drug

    Influenza A virus A/Croatia/10136RV/2023 X-425A (H3N2) antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB21765
    Approved

    This defense includes the production of humoral immunity through the development of antibodies and of cell-mediated immunity through the production of T-lymphocytes.

  9. Drug

    177Lu-PSMA-I&T

    go.drugbank.com/drugs/DB22176
    Investigational

    177Lu-PSMA-I&T is under investigation in clinical trial NCT04886986 (Phase I/II 225Ac-J591 Plus 177Lu-PSMA-I&T for Progressive Metastatic Castration Resistant Prostate Cancer).

    Synonyms: 177Lu-PSMA I&T, 177Lu-PSMA-I&T
  10. Drug

    CTA30X UCAR-T

    go.drugbank.com/drugs/DB24819
    Investigational

    CTA30X UCAR-T is a biologic drug. CTA30X UCAR-T is under investigation in clinical trial NCT05015972 (UCAR-T for CD19+ Refractory/Relapsed B Hematologic Malignancies).

    Synonyms: CTA30X UCAR-T