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Displaying results 541 - 550 of 10000 in total
  1. Drug

    TPX-4589

    go.drugbank.com/drugs/DB18604
    Investigational

    TPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.

    Synonyms: Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE
  2. Drug

    (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one

    go.drugbank.com/drugs/DB07148
    Experimental

    Synonyms: (6S)-1-chloro-3-[(4-fluorobenzyl)oxy]-6-(pyrrolidin-1-ylcarbonyl)pyrrolo[1,2-a]pyrazin-4(6H)-one
  3. Drug

    Anti-CD7 CAR T-cell therapy

    go.drugbank.com/drugs/DB18128
    Experimental

    Synonyms: A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7, Anti-CD7 CAR T-cell therapy
  4. Drug

    ARGX-119

    go.drugbank.com/drugs/DB18133
    Investigational

    ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).

    Synonyms: a fully humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and activates MuSK
  5. Drug

    12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one

    go.drugbank.com/drugs/DB08703
    Experimental

    Synonyms: 12-(2-hydroxyethyl)-2-(1-methylethoxy)-13,14-dihydronaphtho[2,1-a]pyrrolo[3,4-c]carbazol-5(12H)-one
  6. Drug

    (1R,2R,3R,4S,5R)-4-(Benzylamino)-5-(methylthio)cyclopentane-1,2,3-triol

    go.drugbank.com/drugs/DB06984
    Experimental

    Synonyms: Benzylation of mannostatin A, 1b, (1R,2R,3R,4S,5R)-4-(Benzylamino)-5-(methylthio)cyclopentane-1,2,3-triol
  7. Drug

    N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide

    go.drugbank.com/drugs/DB07879
    Experimental

    Synonyms: N-hydroxy-5-[(3-phenyl-5,6-dihydroimidazo[1,2-a]pyrazin-7(8H)-yl)carbonyl]thiophene-2-carboxamide
  8. Drug

    N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine

    go.drugbank.com/drugs/DB08057
    Experimental

    Synonyms: N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine
  9. Drug

    Flubentylosin

    go.drugbank.com/drugs/DB17769
    Investigational

    Synonyms: 4''-(p-fluorobenzyl)tylosin a, 4b-o-((4-fluorophenyl)methyl)tylosin
  10. Drug

    Clofarabine

    go.drugbank.com/drugs/DB00631
    ApprovedInvestigational

    Clofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed.

    Categories: OCT2 Substrates with a Narrow Therapeutic Index, OAT3/SLC22A8 Substrates with a Narrow Therapeutic IndexSynonyms: Cl-F-Ara-A, (2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol