Search
Milnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigationalyet approved the agent for such treatment, citing lack of robust evidence of efficacy, insufficient demonstration of maintenance of effect, and other concerns [F3928, F3934]. … important role in the mitigation of pain signals in the descending inhibitory pain pathways in the brain and spinal cord [A175759, A175843, A175846].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: IXEL 50 MG KAPSUL, 56 ADET, Ixel 50 mg - KapselnDimethyl fumarate
go.drugbank.com/drugs/DB08908ApprovedInvestigationalIt is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … in response to oxidative stress.
Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: DIMETILFUMARATO EG, TECFIDERA 240 MG ENTERIK SERT KAPSÜL,56 ADETInsulin lispro
go.drugbank.com/drugs/DB00046ApprovedInvestigationalDue to its duration of action of around 5 hours, Humalog is considered "bolus insulin" as it provides high levels of insulin in a short period of time to mimic the release of endogenous insulin from the … Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/ml, HUMALOG MIX 25 SUSPENSION FOR INJECTION 100 iu/mlCategories: Drugs Used in Diabetes, Cytochrome P-450 CYP1A2 InducersRosuvastatin
go.drugbank.com/drugs/DB01098ApprovedInvestigational[A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … [A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, rosuvastatin is considered the most potent; doses of 10 to 40mg rosuvastatin per day were
Synonyms: (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acidMixtures: LIPIVAN E ® 10 MG / 10 MG, ROSUVINA LEGRAND® E 10/20Olmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalOlmesartan is commonly used for the management of hypertension and Type 2 Diabetes-associated nephropathy, particularly in patients who are unable to tolerate ACE inhibitors. … The angiotensin II receptor blocker (ARB) family of drugs unique in that it blocks all angiotensin II activity, regardless of where or how it was synthesized.
Mixtures: ILTUXAM ® 20 MG - 10 MG, IMLO 20 MG/10 MG FILM TABLET ,28 ADETCategories: Angiotensin 2 Receptor Blocker, Agents Acting on the Renin-Angiotensin SystemAcyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigational[L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318] … [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old.
Mixtures: Activir Duo 50 mg/g + 10 mg/g Creme, HERPAZON % 5 + % 1 KREM, 5 GRAMCategories: MATE 2 Substrates, Heterocyclic Compounds, 2-RingKetorolac
go.drugbank.com/drugs/DB00465ApprovedInvestigationalKetorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution. … [L6520] Impressively, ketorolac has a similar efficacy to standard doses of morphine and meperidine making it a useful opioid sparing agent.[L6511]
Mixtures: Ixoba M, ONEMER DTCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure . Upon cleavage of its ester group by the liver, benazepril is converted into its acti...
Mixtures: CİBADREX 10/12,5 MG FİLM TABLET, 28 ADET, CİBADREX 5/6,25 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemDocusate
go.drugbank.com/drugs/DB11089ApprovedInvestigationalRecently there has been pressure to stop prescribing docusate as it has been identified as an ineffective medicine[A176972,A176987,L5912]. … Additionally, it does not appear to lessen symptoms associated with constipation such as abdominal cramps. Still docusate is available in over-the-counter products as a common laxative.
Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, Senna Plus Standardized Senna Concentrate 8.6 mg and Docusate Sodium 50 mg EachInternational brands: Docusol 100Prednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InducersSynonyms: 1, 2-Dehydrocortisone, 1,4-Pregnadiene-17α,21-diol-3,11,20-trione