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Briakinumab
go.drugbank.com/drugs/DB05459InvestigationalBriakinumab is a human anti-IL-12 monoclonal antibody being developed for the treatment of a number of T-cell driven autoimmune diseases. … As of 2011 drug development for psoriasis has been discontinued in the U.S. and Europe.
Dexloxiglumide
go.drugbank.com/drugs/DB04856InvestigationalDexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist in phase III testing by Rottapharm in Europe only, as U.S. trials have been discontinued. … As the D-isomer of loxiglumide, it retains all pharmacological properties of loxiglumide but is more potent.
Trandolaprilat
go.drugbank.com/drugs/DB14209ExperimentalThe active metabolite of the prodrug Trandolapril.
Categories: Agents Acting on the Renin-Angiotensin SystemFP-1096
go.drugbank.com/drugs/DB05310ExperimentalFP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect.
Alunacedase alfa
go.drugbank.com/drugs/DB15736InvestigationalAlunacedase alfa is a recombinant and soluble glycosylated form of human ACE2. This recombinant version of the enzyme has antihypertensive and potential antineoplastic activities.
Polyinosinic-polycytidylic acid
go.drugbank.com/drugs/DB16467InvestigationalSynonyms: Poly I-C, Poly(I+C)Categories: Poly I, Poly I-CCadralazine
go.drugbank.com/drugs/DB13452ExperimentalCategories: Arteriolar Smooth Muscle, Agents Acting OnBucetin
go.drugbank.com/drugs/DB13278ApprovedWithdrawnBucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.[A175636]
Tozorakimab
go.drugbank.com/drugs/DB16473InvestigationalTozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions. … moderate-to-severe asthma), NCT04170543 (completed with results; diabetic kidney disease), NCT05624450 (recruiting; viral lung infection requiring supplemental oxygen), NCT05742802 (recruiting; long-term study in
Fidexaban
go.drugbank.com/drugs/DB19562ExperimentalFidexaban is a small molecule drug. The usage of the INN stem '-xaban' in the name indicates that Fidexaban is a blood coagulation factor XA inhibitor, antithrombotic. … Fidexaban has a monoisotopic molecular weight of 526.18 Da.