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Tyrosinase
go.drugbank.com/drugs/DB16626Investigational[A231829, A231839] It is recognized as being the main enzyme responsible for enzymatic browning and melanogenesis in mammals, thus causing undesired browning of fruits and vegetables and diseases resulting … [A231829, A231834, A231839] It is responsible for producing melanin pigment across the phylogenetic spectrum.
SVV-001
go.drugbank.com/drugs/DB06129InvestigationalSVV-001 has also demonstrated cancer-killing specificity 10,000 times higher than that of traditional chemotherapeutics with no overt toxicity at doses one million times higher than effective doses in … SVV-001 is investigated for use/treatment in cancer/tumors and lung cancer. SVV-001 is a solid.
Ceftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedIt is resistant to hydrolysis by beta-lactamase, and has activity against both Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. … It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product.
Placental Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15730InvestigationalIt was also found that fetal-side pMSCs express different surface markers. … It can be obtained relatively easily as medical waste from which MSCs can be non-invasively extracted and without the ethical issues that come with embryonic stem cells.
HMI-203
go.drugbank.com/drugs/DB18520InvestigationalHMI-203 is an investigational gene therapy developed by Homology Medicines, Inc. … It consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS).
Bencyclane
go.drugbank.com/drugs/DB13488ExperimentalA vasodilator agent found to be effective in a variety of peripheral circulation disorders. It has various other potentially useful pharmacological effects.
Synonyms: 3-((1-Benzylcycloheptyl)oxy)-N,N-dimethylpropylaminFlorzolotau F-18
go.drugbank.com/drugs/DB16297InvestigationalPMPBB3 F-18 is under investigation in clinical trial NCT04305210 (Alzheimer's Disease: Clinical Investigation and Neuroimage Studies Including 18F-PM-PBB3 and 18f-florbetapir (AV-45) PET Examination).
Galicaftor
go.drugbank.com/drugs/DB14894InvestigationalGalicaftor is under investigation in clinical trial NCT03540524 (A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 … in Patients With Cystic Fibrosis.).
Nanoparticle Epirubicin
go.drugbank.com/drugs/DB16248InvestigationalIt is a novel [epirubicin] drug-conjugated polymeric micelle. … Nanoparticle Epirubicin is under investigation in clinical trial NCT03168061 (Dose-escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma).