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Displaying results 5521 - 5530 of 10000 in total
  1. Target

    Cyclopropane mycolic acid synthase MmaA2

    go.drugbank.com/bio_entities/BE0002512
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine. MmaA2 also catalyzes the biosynthesis of the cis-cyc...

    Synonyms: SAM-MT
  2. Target

    Tyrosine-protein kinase STYK1

    go.drugbank.com/bio_entities/BE0015530
    TargetHumans

    Probable tyrosine protein-kinase, which has strong transforming capabilities on a variety of cell lines. When overexpressed, it can also induce tumor cell invasion as well as metastasis in distant organs. May act by activating both MAP k...

    Synonyms: NOK
  3. Drug

    Melanoma antigen recognized by T-cells 1

    go.drugbank.com/drugs/DB15081
    Investigational

    Melanoma antigen recognized by T-cells 1 is under investigation in clinical trial NCT01748747 (Vaccine Therapy and Resiquimod in Treating Patients With Stage II-IV Melanoma That Has Been Removed By Surgery

    Synonyms: Melanoma antigen recognized by T-cells 1
  4. Drug

    LX6171

    go.drugbank.com/drugs/DB05180
    Investigational

    LX6171 is an oral drug candidate that was generated by Lexicon medicinal chemists and is being developed to treat disorders characterized by cognitive impairment, such as Alzheimer's disease, schizophrenia

  5. Drug

    CRx-401

    go.drugbank.com/drugs/DB05775
    Experimental

    Unlike other NSAIDs, or non-steroidal anti-inflammatory drugs, the dose of diflunisal in CRx-401 has demonstrated in preclinical studies the ability to synergistically enhance the anti-diabetic effects … It consists of a low dose of the analgesic diflunisal in conjunction with a modified-release therapeutic dose of bezafibrate, an anti-cholesterol agent.

  6. Indication

    Medication Resistant Epilepsy

    go.drugbank.com/conditions/DBCOND0117829
    Drugs: Diazepam
    Synonyms: Epilepsy NOS, Epilepsy, NOS
  7. Drug

    Ezatiostat

    go.drugbank.com/drugs/DB05460
    Investigational

    These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen … It acts intracellularly on the MAPK signaling pathway by activating ERK2.

  8. Drug

    Ancitabine

    go.drugbank.com/drugs/DB20595
    Experimental

    Ancitabine has a monoisotopic molecular weight of 225.07 Da. … The usage of the INN stem '-citabine' in the name indicates that Ancitabine is a nucleoside antiviral or antineoplastic agent, cytarabine or azacitidine derivative.

  9. Drug

    Galocitabine

    go.drugbank.com/drugs/DB21373
    Experimental

    Galocitabine has a monoisotopic molecular weight of 439.14 Da. … The usage of the INN stem '-citabine' in the name indicates that Galocitabine is a nucleoside antiviral or antineoplastic agent, cytarabine or azacitidine derivative.

  10. Indication

    Carcinoid Tumors

    go.drugbank.com/conditions/DBCOND0030495
    Drugs: Pentetreotide
    Synonyms: Carcinoid tumour NOS, Carcinoid tumour no ICD-O subtype