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Oleoyl-estrone
go.drugbank.com/drugs/DB04870InvestigationalOleoyl-estrone (OE) is a fatty acid ester of estrone. This hormone occurs naturally and is found circulating in various animal species and humans. It has been shown in animal studies to promote the loss of body fat while maintaining body...
Efonidipine
go.drugbank.com/drugs/DB09235InvestigationalEfonidipine is a calcium channel blocker of the dihydropyridine class, commercialized by Shionogi & Co. (Japan). Initially, it was marketed in 1995 under the trade name, Landel. The drug has been shown to block T-type in addition to ...
Marimastat
go.drugbank.com/drugs/DB00786InvestigationalUsed in the treatment of cancer, Marmiastat is an angiogenesis and metastasis inhibitor. As an angiogenesis inhibitor it limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from brea...
Eldecalcitol
go.drugbank.com/drugs/DB05295InvestigationalEldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral dens...
FP-1096
go.drugbank.com/drugs/DB05310ExperimentalFP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect.
Elesclomol
go.drugbank.com/drugs/DB05719InvestigationalElesclomol is a novel, injectable, drug candidate that kills cancer cells by elevating oxidative stress levels beyond a breaking point, triggering programmed cell death. In preclinical models elesclomol showed potent killing of a broad r...
AD 337
go.drugbank.com/drugs/DB05725InvestigationalAD 337 was under investigation in clinical trial NCT00377039 (A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia). The drug was created by Sosei pharmaceuticals to treat Fibromyalgia in fe...
Seletracetam
go.drugbank.com/drugs/DB05885InvestigationalSeletracetam is a pyrrolidone derivative and with a structural similarity to newer generation antiepileptic drug levetiracetam. It binds to the same target as levetiracetam but with higher affinity and has shown potent seizure suppressio...
Totrombopag
go.drugbank.com/drugs/DB05930InvestigationalSB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets. This drug is developed by GlaxoSmithKline and used to treat Thrombocytopenia.Th...