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Fludiazepam
go.drugbank.com/drugs/DB01567IllicitInvestigationalIt is a scheduled drug in the U.S., but is approved for use in Japan.
Sparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnSparteine is not currently FDA-approved for human use, and its salt, sparteine sulfate, is one of the products that have been withdrawn or removed from the market for reasons of safety or effectiveness … It is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents.
TEL540-548
go.drugbank.com/drugs/DB17461InvestigationalTEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT).
Uridine monophosphate
go.drugbank.com/drugs/DB03685InvestigationalA uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
XL999
go.drugbank.com/drugs/DB05014InvestigationalXL999 has the potential to provide benefit to patients with lung cancer and acute myelogenous leukemia. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.
IMCY-0141
go.drugbank.com/drugs/DB17019InvestigationalIMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of multiple sclerosis (MS) and the destruction of the myelin … sheath protecting the nerves.
GMK
go.drugbank.com/drugs/DB06661ExperimentalGMK vaccine (a ganglioside conjugate vaccine coupled to keyhole limpet hemocyanin and formulated with the adjuvant QS-21) for the potential treatment of melanoma
Seractide acetate
go.drugbank.com/drugs/DB09334ApprovedSeractide acetate is the acetate salt of full length human corticotropin.
Pozanicline
go.drugbank.com/drugs/DB05458InvestigationalABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity … In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR subtypes.
Maxy-G34
go.drugbank.com/drugs/DB05718Investigational, while Neulasta has a single 20 Kd PEG group attached at the N terminal end of the wild type G-CSF protein. … wild type human G-CSF to avoid PEGylation of such sites.