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Displaying results 5541 - 5550 of 10000 in total
  1. Drug

    Elesclomol

    go.drugbank.com/drugs/DB05719
    Investigational

    In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high doses, and an ability to strongly enhance the efficacy of certain chemotherapy agents, with minimal

  2. Drug

    NBI-6024

    go.drugbank.com/drugs/DB05819
    Investigational

    NBI-6024 is an altered peptide ligand that is designed to cause an immune response which result in preservation of beta-cell function and endogenous insulin production.

  3. Drug

    Covid-19 Coronavirus Artificial Antigen Presenting Cell Vaccine

    go.drugbank.com/drugs/DB15813
    Investigational

    Through analysis of potential immunogenic targets of the SARS-Cov2 genome, a synthetic ‘minigene’ was developed using domains of viral structural proteins and a polyprotein protease. … Specifically, the COVID-19 infection relies on the binding of the Spike protein to an ACEII receptor, and with the described approach, the vaccine uses these engineered minigenes to express viral proteins

  4. Drug

    Heptabarbital

    go.drugbank.com/drugs/DB01354
    Experimental

    Heptabarbital is an intermediate or short term barbiturate used mainly for sedation and hypnosis.

  5. Drug

    Pamiparib

    go.drugbank.com/drugs/DB14769
    Investigational

    on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy). … Pamiparib is under investigation in clinical trial NCT03933761 (Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression

  6. Drug

    Padoprazan

    go.drugbank.com/drugs/DB21689
    Experimental

    The usage of the INN stem '-prazan' in the name indicates that Padoprazan is a proton pump inhibitor, not dependent on acid activation. Padoprazan has a monoisotopic molecular weight of 405.12 Da.

  7. Drug

    Bifunctional epoxide hydrolase 2

    go.drugbank.com/drugs/DB15139
    Investigational

    Bifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients

  8. Drug

    Cintirorgon

    go.drugbank.com/drugs/DB20916
    Investigational

    Cintirorgon is under investigation in clinical trial NCT02929862 (Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer). … Cintirorgon has a monoisotopic molecular weight of 603.12 Da.

  9. Drug

    Coumazoline

    go.drugbank.com/drugs/DB21226
    Experimental

    The usage of the INN stem '-azoline' in the name indicates that Coumazoline is a antihistaminic or local vasoconstrictor, antazoline derivative. … Coumazoline has a monoisotopic molecular weight of 228.13 Da.

  10. Drug

    Domazoline

    go.drugbank.com/drugs/DB19937
    Experimental

    The usage of the INN stem '-azoline' in the name indicates that Domazoline is a antihistaminic or local vasoconstrictor, antazoline derivative. … Domazoline has a monoisotopic molecular weight of 248.15 Da.