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Displaying results 5601 - 5610 of 10000 in total
  1. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes

    Synonyms: A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS, EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA)
  2. Drug

    Luminol

    go.drugbank.com/drugs/DB18536
    Experimental

    Synonyms: 3-aminophthalic hydrazide, O-aminophthalylhydrazideCategories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household setting
  3. Drug

    Myristyl glyceryl ether

    go.drugbank.com/drugs/DB15662
    Investigational

    Synonyms: 3-Tetradecyloxy-1,2-propanediol, 1-o-tetradecylglycerol
  4. Drug

    Soneclosan

    go.drugbank.com/drugs/DB04393
    Experimental

    Synonyms: 5-chloro-2-(p-chlorophenoxy)phenol
  5. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors. … It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015.

    Categories: MATE 2 Inhibitors, Heterocyclic Compounds, 2-RingProducts: REXULTI (BREXPIPRAZOLE) TABLETS 2 MG, REXULTI (BREXPIPRAZOLE) TABLETS 3 MG
  6. Drug

    Triamcinolone

    go.drugbank.com/drugs/DB00620
    ApprovedInvestigationalVet approved

    [L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957. … [L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.

    Synonyms: 9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, 11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dioneInternational brands: Omcilon-A
  7. Drug

    Maleic acid

    go.drugbank.com/drugs/DB04299
    Investigational

    Synonyms: (Z)-2-butenedioic acid, cis-but-2-enedioic acid
  8. Drug

    Diglyme

    go.drugbank.com/drugs/DB02935
    Experimental

    Synonyms: di(2-methoxyethyl) ether, bis(2-methoxyethyl) ether
  9. Drug

    Mecasermin

    go.drugbank.com/drugs/DB01277
    ApprovedInvestigational

    The rhIGF-1 protein is synthesized in bacteria (E. coli) that have been modified by the addition of the gene for human IGF-1. … IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges and a molecular weight of 7649 daltons.

    Categories: Recombinant Human Insulin-like Growth Factor-1Synonyms: RH-OLIGOPEPTIDE-2, VEXXON-IGF-1
  10. Drug

    Marnetegragene autotemcel

    go.drugbank.com/drugs/DB17595
    Approved

    Severe leukocyte adhesion deficiency-I (LAD-I) is a genetic disorder leading to frequent life-threatening infections and high fatality risks among affected pediatric patients. … [L56116, A275467] Allogeneic hematopoietic stem cell transplant is a curative option but is limited by issues such as donor availability, a high incidence of graft-versus-host disease, and graft failure

    Synonyms: Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene, Autologous CD34+ cells transduced ex vivo with a lentiviral vector (Chim-CD18-WPRE) encoding the ITGB2 gene