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Displaying results 5651 - 5660 of 10000 in total
  1. Drug

    GTP-506

    go.drugbank.com/drugs/DB17682
    Experimental

    the desired genetic correction. … GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide

  2. Drug

    Atuliflapon

    go.drugbank.com/drugs/DB19029
    Investigational

    Atuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).

  3. Drug

    Human interferon omega-1

    go.drugbank.com/drugs/DB05472
    Investigational

    The biological activities of IFN-omega 1 and its physiological role are not known to date. … It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering.

  4. Drug

    Phelimin

    go.drugbank.com/drugs/DB18332
    Experimental

    Phelemin (PHE-MIP) is a methacrylic acid-based copolymer purified to bind to L-phenylalanine and L-phenylalanine-containing peptides. … [L48151] It is under investigation for the treatment of hyperphenylalaninemia.

  5. Drug

    Sonelokimab

    go.drugbank.com/drugs/DB18843
    Investigational

    Sonelokimab is under investigation in clinical trial NCT06411379 (Study to Evaluate the Efficacy and Safety of Subcutaneous Sonelokimab Compared With Placebo in Adult Participants With Moderate to Severe

  6. Drug

    IDM-2

    go.drugbank.com/drugs/DB05293
    Experimental

    IDM produces MAK cells from the patient's own white blood cells by activating these cells ex vivo to allow them to recognize and destroy tumor cells.

  7. Drug

    3-(5-Amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid

    go.drugbank.com/drugs/DB08668
    Experimental

    This compound belongs to the aminobenzoic acid derivatives. … These are benzoic acids (or derivatives thereof) containing an amine group attached to the benzene moiety. 3-(5-amino-3-imino-3H-pyrazol-4-ylazo)-benzoic acid targets the protein methionine aminopeptidase

  8. Drug

    Carbarsone

    go.drugbank.com/drugs/DB11382
    ExperimentalVet approved

    It belongs to the _organoarsenic_ group of chemical compounds and has antiamebic properties. … It is also used as a food additive with the goal of increasing weight gain and controlling the occurrence of blackhead disease in chicken and turkeys.

  9. Drug

    Mizacorat

    go.drugbank.com/drugs/DB21458
    Investigational

    The usage of the INN stem '-corat' in the name indicates that Mizacorat is a glucocorticoid receptor agonist. … Mizacorat is under investigation in clinical trial NCT04556760 (Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared to Prednisolone, in Adults With Type 2 Diabetes

  10. Drug

    Otelixizumab

    go.drugbank.com/drugs/DB05496
    Investigational

    Otelixizumab is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. … Otelixizumab is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance