Search
Chlormerodrin Hg-197
go.drugbank.com/drugs/DB09406ApprovedChlormerodrin Hg-197 is a radiolabelled form of chlormerodrin, an organomercury compound that was previously used as a diuretic. Its radiolabelled form was used as diagnostics in brain scans.
Isradipine
go.drugbank.com/drugs/DB00270ApprovedIt is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. … It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: OPTASIL ®, CALBLOCK® TABLETASZilpaterol
go.drugbank.com/drugs/DB11479ExperimentalVet approvedZilpaterol is a β2 adrenergic agonist sold under the trade name, Zilmax, produced by Intervet, a subsidiary of Merck & Co. … Zilpaterol is typically fed to cattle in the last three to six weeks of life with a brief washout period to clear the drug from the tissues before slaughter.
Categories: Heterocyclic Compounds, 2-RingIsoxsuprine
go.drugbank.com/drugs/DB08941ApprovedWithdrawnIt is used in the treatment of peripheral vascular disease and in premature labor. … A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.
Categories: 2-Amino-1-Phenylethanol DerivativesFluoride ion
go.drugbank.com/drugs/DB11257ApprovedInvestigationalHaving a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element.
Mixtures: Tri-Vi-Flor, Poly-Vi-Flor with IronTrichloroethylene
go.drugbank.com/drugs/DB13323ApprovedTrichloroethylene is a halocarbon commonly used as an industrial solvent, not to be confused with the similar 1,1,1-trichloroethane, also known as chlorothene. … Environmental exposure, particularly groundwater and drinking water contamination from industrial discharge, is a major concern for human health and has been the subject of numerous incidents and lawsuits
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 1,1-dichloro-2-chloroethyleneMethylprednisolone
go.drugbank.com/drugs/DB00959ApprovedInvestigationalVet approvedMethylprednisolone is a [prednisolone] derivative glucocorticoid with higher potency than [prednisone].[A188811] It was first described in the literature in the late 1950s. … [A192813] The efficacy of methylprednisolone in novel coronavirus pneumonia is being investigated further in clinical trials.[L12666]
Mixtures: P-Care D80, P-Care D40Categories: Corticosteroids, Weak (Group I), P-glycoprotein inducersEptifibatide
go.drugbank.com/drugs/DB00063ApprovedInvestigationalDerived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide that belongs to the class of arginin-glycin-aspartat-mimetics.
Products: INTEGRILIN INYECTABLE 2 MG/ML., INTEGRILIN IV BOLUS INJECTION 2 mg/mlZytron
go.drugbank.com/drugs/DB11768ApprovedWithdrawnZytron (DMPA) is under investigation for the treatment and health services research of HIV, Lactation, Contraception, Postpartum Depression, and Immune Cells (Mucosal and Systemic).
Synonyms: O-(2,4-dichlorophenyl)-O-methyl-isopropylphosphoramidothioate