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Displaying results 561 - 570 of 10000 in total
  1. Drug

    Sulfinpyrazone

    go.drugbank.com/drugs/DB01138
    Approved

    A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.

    Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine, 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione
  2. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Synonyms: (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine, (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamineInternational brands: Animex-On
  3. Drug

    Norethisterone

    go.drugbank.com/drugs/DB00717
    ApprovedInvestigational

    as an oral contraceptive until 1962. … [L9527,L10301,L10304,L10307] First derived in 1951 in Mexico City, norethisterone was originally intended for use as a remedy for irregular menstruation and endometriosis, and was not marketed for use

    Synonyms: 17-hydroxy-19-nor-17-α-pregn-4-en-20-yn-3-one, 17-hydroxy-19-nor-17α-pregn-4-en-20-yn-3-oneInternational brands: Primolut-N
  4. Indication

    Gaucher Disease, Type 1

    go.drugbank.com/conditions/DBCOND0035324
    Drugs: Eliglustat · Imiglucerase · Taliglucerase alfa · Velaglucerase alfa
    Synonyms: Type I Gaucher Disease, Gaucher Disease, Type I
  5. Indication

    Scheie Syndrome

    go.drugbank.com/conditions/DBCOND0031182
    Drugs: Laronidase
    Synonyms: MPS I, Mucopolysaccharidosis I
  6. Drug

    Anti-CD19 CAR-T cells

    go.drugbank.com/drugs/DB21913
    Investigational

    CD19 CAR-T is under investigation in clinical trial NCT05618041 (The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients with Hematological Malignancies).

    Synonyms: CD19 CAR T, CD19 CAR-T
  7. Drug

    5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07140
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  8. Drug

    Diosmin

    go.drugbank.com/drugs/DB08995
    ApprovedInvestigational

    Compression and pharmacotherapy are frequently used to manage chronic venous insufficiency, improving circulation and symptoms of venous disease. … Chronic venous insufficiency is a common condition the western population.

    Mixtures: NA, VENADOL® FCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  9. Indication

    Gargoylism, Hurler Syndrome

    go.drugbank.com/conditions/DBCOND0074037
    Drugs: Laronidase
    Synonyms: MPS I H, MPS I
  10. Drug

    TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE

    go.drugbank.com/drugs/DB07013
    Experimental

    Synonyms: TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE