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Peppermint oil
go.drugbank.com/drugs/DB11198ApprovedInvestigationalDue to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized … It is also an active ingredient in topical analgesics for the relief of joint and muscle pain. Peppermint oil can be applied topically to temporarily relieve tension-type headache.
Mixtures: Sinsinpas Arex Instant Pain Relief (not for Sale), The Natural Dentist Peppermint SageCategories: Drugs for Functional Gastrointestinal DisordersRituximab
go.drugbank.com/drugs/DB00073ApprovedInvestigationalFDA in 1997 as a single agent to treat patients with B-cell Non-Hodgkin's Lymphoma (NHL) [L4811], however, has now been approved for a variety of conditions [FDA label]. … It was originally approved by the U.S.
Categories: Biologics for Rheumatoid Arthritis TreatmentProducts: Mabthera Concentrate for Solution for Infusion 100mg/10ml, TRUXIMA® CONCENTRATE FOR SOLUTION FOR INFUSION 10MG/MLAvelumab
go.drugbank.com/drugs/DB11945ApprovedInvestigational[A261496] On September 18 and December 18 of the same year, it was also granted approval by EMA [L48126] and Health Canada,[L48171] respectively. … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells.
Products: BAVENCIO CONCENTRATE FOR SOLUTION FOR INFUSION 200MG/10ML, BAVENCIO 200 mg/10mL concentrate for solution for infusionCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Categories: Detoxifying Agents for Antineoplastic Treatment, Compounds used in a research, industrial, or household settingProducts: Mesna for Injection, CONCENTRATE SOLUTION FOR INJECTION 400MG/4MLAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[A235103,A235118] Amivantamab was found to be more effective than the EGFR inhibitor [erlotinib] or the MET inhibitor [crizotinib] _in vivo_. … Amivantamab, also known as JNJ-61186372, is an anti-EGFR-MET bispecific antibody, derived from Chinese hamster ovary cells, approved for the treatment of adult patients with locally advanced or metastatic
Products: RYBREVANT 350mg/7mL Concentrate for Solution for InfusionSulfur hexafluoride
go.drugbank.com/drugs/DB11104ApprovedInvestigationalSulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border … in adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients
Products: SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/mlCabazitaxel
go.drugbank.com/drugs/DB06772ApprovedInvestigational[A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel]. … [A7056, A260421, A260621] Cabazitaxel is used to treat metastatic castration-resistant prostate cancer. It was first approved by the FDA on June 17, 2010.
Products: JEVTANA 60mg CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION, JEVTANA (CONCENTRATE AND SOLVENT FOR SOLUTION FOR INFUSION)Doripenem
go.drugbank.com/drugs/DB06211ApprovedWithdrawnThe FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved indications. … Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Powder for Injection 500mg, DORIBAX 500 MG (Doripenem) for InjectionAnthrax vaccine
go.drugbank.com/drugs/DB11003ApprovedInvestigationalAnthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to *Bacillus anthracis*. … [L47566, L47561] These vaccines are currently stored in the Strategic National Stockpile in preparation for an Anthrax terrorist attack or for pre-exposure prophylaxis of personnel going to specific arenas
Products: BioThrax (Anthrax Vaccine Adsorbed) Supension for Injection 50?g/dose (nominal)Daratumumab
go.drugbank.com/drugs/DB09331ApprovedInvestigational[L13290,L13296] A subcutaneous formulation of daratumumab co-formulated with hyaluronidase-fihj is also approved for the treatment of adults with multiple myeloma. … Daratumumab is an immunoglobulin G1 kappa monoclonal antibody developed by Janssen and Genmab.
Products: DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 100MG/5ML