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AVR-RD-02
go.drugbank.com/drugs/DB17650InvestigationalIt consists of autologous CD34+ enriched hematopoietic stem cells (HSCs) that have been genetically modified _ex vivo_ with a lentiviral vector (LV) to contain a ribonucleic acid (RNA) transcript that, … after reverse transcription, results in codon-optimized, complementary deoxyribonucleic acid (cDNA) that, upon its integration into human genome, encodes for functional human glucocerebrosidase (GCase
Poloxamer 188
go.drugbank.com/drugs/DB11333ApprovedComposed of two hydrophilic side-chains attached to a hydrophobic center core [A27218], its average molecular weight is 8400 Daltons. … The ability of P188 in attenuating membrane damage and cell injury has been demonstrated in a variety of _in vivo_ and _in vitro_ models [A27218].
Categories: Compounds used in a research, industrial, or household settingCalcium silicate
go.drugbank.com/drugs/DB13829InvestigationalCategories: Drugs for Acid Related Disordersp-Phenylenediamine
go.drugbank.com/drugs/DB14141ApprovedCategories: Compounds used in a research, industrial, or household settingRecombinant Super-Compound Interferon
go.drugbank.com/drugs/DB15752InvestigationalRecombinant super-compound interferon (rSIFN-co) is a recombinant version of interferon alpha with modified spatial configuration. This interferon has antiviral and antitumor activity.
TG-100801
go.drugbank.com/drugs/DB05075InvestigationalTG100801 is a topically applied kinase inhibitor in macular degeneration patients.
Vactosertib
go.drugbank.com/drugs/DB15310InvestigationalVactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).
Synonyms: 2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]anilineQuisinostat
go.drugbank.com/drugs/DB12985InvestigationalQuisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia.