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Saposin C
go.drugbank.com/drugs/DB17380InvestigationalBXQ-350 consists of Saposin C and the phospholipid dioleoylphosphatidyl-serine (DOPS), a phospholipid located on cell membranes. … Recombinant, non-glycosylated Saposin C is an active ingredient of BXQ-350, which is a novel, investigational anti-neoplastic therapy.
Plamotamab
go.drugbank.com/drugs/DB18944InvestigationalPlamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (
Oleic Acid
go.drugbank.com/drugs/DB04224ApprovedInvestigationalVet approvedIt is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)
Bertilimumab
go.drugbank.com/drugs/DB05429InvestigationalIt is developed by MedImmune for the treatment of Allergic Rhinitis. … Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development.
AX200
go.drugbank.com/drugs/DB05093Investigationalthrough the induction of neuro- and arteriogenesis and supporting the reorganisation of the nervous system. … AX200, which has been developed for the treatment of stroke, is the most advanced drug candidate and is halfway through the process of gaining clinical approval.
Palifosfamide
go.drugbank.com/drugs/DB05668InvestigationalPalifosfamide (ZIO-201) is a proprietary stabilized metabolite of ifosfamide. Ifosfamide has been shown to be effective in high doses in treating testicular cancer, sarcoma and lymphoma.
BF-1
go.drugbank.com/drugs/DB06029ExperimentalBF-1 is an investigational 5-HT2B receptor antagonist developed for the prophylaxis of Migraines.
Glembatumumab vedotin
go.drugbank.com/drugs/DB05996InvestigationalA conjugate of an anti-glycoprotein non-metastatic melanoma protein B mAb and monomethyl auristatin E for the treatment of melanoma and breast cancer.
OXI-4503
go.drugbank.com/drugs/DB05143InvestigationalPreclinical studies have demonstrated that OXI-4503 has (i) single-agent activity against a range of xenograft tumor models; and (ii) synergistic or additive effects when incorporated in various combination … metabolized by oxidative enzymes (e.g., tyrosinase and peroxidases), which are elevated in many solid tumors and tumor infiltrates, to an orthoquinone chemical species that has direct cytotoxic effects on
Trestolone
go.drugbank.com/drugs/DB05830InvestigationalIn males, regular administration of sufficient quantities of trestolone induces a state of temporary infertility.
Synonyms: 7alpha-Methyl-3-oxo-4-estren-17beta-ol