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PX-12
go.drugbank.com/drugs/DB05448Investigationaltumor growth in animal models. … Since high levels of Trx-1 have been associated with colorectal, gastric and lung cancers, PX-12 is indicated as a potential cancer treatment in combination with chemotherapy for patients with advanced
Talacotuzumab
go.drugbank.com/drugs/DB14796InvestigationalIt is under investigation in clinical trial NCT01632852 (A Study of CSL362 in Patients With CD123+ Acute Myeloid Leukemia Currently in Remission). … Talacotuzumab is an IgG1 monoclonal antibody directed toward the IL3 receptor α–subunit, also known as CD123.
Afimoxifene
go.drugbank.com/drugs/DB04468InvestigationalIt is being developed by Ascent Therapeutics. … TamoGel is formulated using Enhanced Hydroalcoholic Gel (EHG) Technology. This technology enables percutaneous delivery of drugs that cannot be delivered orally.
Vapendavir
go.drugbank.com/drugs/DB05181InvestigationalBTA798 is an antiviral for the treatment of HRV, the common cold virus, known to cause significant clinical complications in sufferers of Asthma and Chronic Obstructive Pulmonary Disease.
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedHalofuginone is a low molecular weight quinazolinone alkaloid, and a potent inhibitor of collagen alpha1(I) and matrix metalloproteinase 2 (MMP-2) gene expression. … Collgard Biopharmaceuticals is developing halofuginone for the treatment of scleroderma and received orphan drug designation from the U.S. Food and Drug Administration in March, 2000.
IDD-1
go.drugbank.com/drugs/DB05439ExperimentalEladem (IDD-1) is a therapeutic vaccine consisting of dendritophages that are loaded in vitro with tumor antigens and then reinjected into the subject.
Sulfabenzamide
go.drugbank.com/drugs/DB09355ApprovedWithdrawnSulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.
OSI-7904L
go.drugbank.com/drugs/DB05457InvestigationalOSI-7904L is a liposome encapsulated thymidylate synthase inhibitor, which is indicated for use in advanced gastric and/or gastroesophageal adenocarcinoma (A-G/GEJA).
Oxandrolone
go.drugbank.com/drugs/DB00621ApprovedInvestigationalA synthetic hormone with anabolic and androgenic properties.