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ABX-PTH

This drug targets and neutralizes the action of parathyroid hormone (PTH) for the treatment of a secondary hyperparathyroidism. … ABX-PTH is a fully human monoclonal antibody generated by Abgenix's technology platform.

Lufotrelvir

PF-07304814 is a small molecule prodrug that targets the 3CL^pro protease (M^pro), which is used by viruses like SARS-CoV-2 to assemble and multiply[L31718]. … Phase 1b studies are also exploring the safety and tolerability of PF-07304814 in COVID-19 patients who are hospitalized (NCT04535167).

Oryctolagus cuniculus hair

European rabbit hair is used in allergenic testing.

Zebularine

Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. … It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.

Zenarestat

Elesclomol

In preclinical models elesclomol showed potent killing of a broad range of cancer cell types at high doses, and an ability to strongly enhance the efficacy of certain chemotherapy agents, with minimal … It is being developed by Synta Pharmaceuticals.

RG2417

The rationale for uridine therapy in neuropsychiatric disorders is supported by preclinical and clinical research. … RG2417 is a proprietary formulation of uridine, a biological compound essential for the synthesis of DNA and RNA, the basic hereditary material found in all cells, and numerous other factors essential

Metyrapone

An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.

Octopamine

It has been used as a nootropic, and therefore it and all of its enantiomer are prohibited by the World Anti-doping Agency (WADA) as of 2014.

Vibriolysin

It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds. … Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus.