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VXA-CoV2-1
go.drugbank.com/drugs/DB16433InvestigationalThis oral vaccine aims to induce immunogenicity through induction of potent serum neutralizing antibodies to the SARS-CoV-2 spike protein, induction of mucosal immune responses, and induction of T-cell … responses to both vaccine antigens of the SARS-CoV-2 nucleocapsid and spike proteins[L30498].
AT-7519
go.drugbank.com/drugs/DB08142InvestigationalAT7519 is a selective inhibitor of certain Cyclin Dependent Kinases (CDKs) leading to tumour regression. It is developed by Astex for the treatment of solid tumours and haematological malignancies.
Synonyms: 4-{[(2,6-dichlorophenyl)carbonyl]amino}-N-piperidin-4-yl-1H-pyrazole-3-carboxamideCategories: Heterocyclic Compounds, 1-RingN(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acid
go.drugbank.com/drugs/DB03458ExperimentalN(4)-adenosyl-n(4)-methyl-2,4-diaminobutanoic acid is a solid. This compound belongs to the purine nucleosides and analogues. These are compounds comprising a purine base attached to a sugar.
Synonyms: 5'-{[(3S)-3-Amino-3-carboxypropyl](methyl)amino}-5'-deoxyadenosine, N(4)-Adenosyl-N(4)-methyl-2,4-diaminobutanoic acidEquus caballus dander
go.drugbank.com/drugs/DB11021ApprovedEquus caballus dander is the dander of Equus caballus. Equus caballus dander is used in allergenic testing.
Theralizumab
go.drugbank.com/drugs/DB15717InvestigationalAfter the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532] … Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer.
Glycochenodeoxycholic Acid
go.drugbank.com/drugs/DB02123ExperimentalA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. … It is a cholagogue and choleretic. [PubChem]
Categories: N-substituted Glycines, Compounds used in a research, industrial, or household settingL-cysteic acid
go.drugbank.com/drugs/DB03661ExperimentalIt occurs normally in the outer part of the sheep's fleece, where the wool is exposed to light and weather. … L-cysteic acid is a beta-sulfoalanine. It is an amino acid with a C-terminal sulfonic acid group which has been isolated from human hair oxidized with permanganate.
Synonyms: 3-sulfo-L-alanine, 2-Amino-3-sulfopropionic acidCortisone
go.drugbank.com/drugs/DB14681InvestigationalIt is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726) … A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive.
Synonyms: Kendall's compound E, Wintersteiner's compound FCategories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersATX-201
go.drugbank.com/drugs/DB05765InvestigationalATX-201 is one of a family of novel compounds that inhibits microtubule polymerization. It is developed by Kythera Biopharmaceuticals, Inc. for the treatment of actinic keratosis. … The company announced the decision to discontinue its ATX-201 clinical program for actinic keratosis.
Allocetra
go.drugbank.com/drugs/DB16424Investigationalso that the immune system is rebalanced back to normal -- averting a cytokine storm. … Allocetra is a novel therapy where billions of early apoptotic cells are infused into the bloodstream of a patient, using the body's own natural regulation mechanisms to rebalance an unbalanced immune