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Displaying results 5771 - 5780 of 10000 in total
  1. Drug

    BHV-1300

    go.drugbank.com/drugs/DB22673
    Investigational

    BHV-1300 is a IgG1,2,4 selective degrader being investigated for the treatment of Grave's disease.

  2. Drug

    Linsitinib

    go.drugbank.com/drugs/DB06075
    Investigational

    An orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. … IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis.

  3. Drug

    KAND567

    go.drugbank.com/drugs/DB16511
    Investigational

    KAND567, a small molecule, blocks the fractaline (CX3CL1) receptor, which mediates the immune system response to inflammation . Because COVID-19 involves cytotoxic cells associated with this pathway, KAND567 is currently being tested as ...

  4. Drug

    Irsogladine

    go.drugbank.com/drugs/DB13056
    Investigational

    Irsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Bizelesin

    go.drugbank.com/drugs/DB12352
    Investigational

    Bizelesin has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Imeglimin

    go.drugbank.com/drugs/DB12509
    Investigational

    Imeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus.

    Categories: Drugs Used in Diabetes
  7. Drug

    KF-0210

    go.drugbank.com/drugs/DB17476
    Investigational

    It is being investigated for cancers.

  8. Drug

    RGX-181

    go.drugbank.com/drugs/DB17942
    Experimental

    Developed by REGENXBIO, it is being investigated for the treatment of late-infantile neuronal ceroid lipofuscinosis type 2 (CLN2) disease.[L47072] … RGX-181 consists of an adeno-associated virus serotype 9 (AAV9) vector designed to deliver the soluble lysosomal enzyme tripeptidyl peptidase I (TPP1) gene.

  9. Drug

    Gavestinel

    go.drugbank.com/drugs/DB06741
    Experimental

    Gavestinel displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites and is orally bioavailable and active in vivo. … Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM).

  10. Drug

    Sorbitan monooleate

    go.drugbank.com/drugs/DB19493
    Experimental

    Sorbitan monooleate is a small molecule drug. Sorbitan monooleate has a monoisotopic molecular weight of 428.31 Da.

    Categories: Compounds used in a research, industrial, or household setting