Gavestinel

DB06741ExperimentalSmall molecule

Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM). Gavestinel displays > 1000-fold selectivity over NMDA, AMPA...

Formula / weight: C₁₈H₁₂Cl₂N₂O₃ · 375.21 g/mol (avg)
Code names: GV-150,526A · GV-150526X

Resolves to

Compound

UNII318X4QY113CAS153436-22-7ChEMBLCHEMBL44793PubChem6450546

Structure

InChIKeyWZBNEZWCNKUOSM-VOTSOKGWSA-NSMILESOC(=O)C1=C(\C=C\C(=O)NC2=CC=CC=C2)C2=C(Cl)C=C(Cl)C=C2N1

Targets

P48167GLRBO75311GLRA3P23416GLRA2P23415GLRA1

What you can answer from here — as of August 30, 2026

5Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

61Drug interactionsStructured to mechanism, not free text

10+ReferencesStructured and connected to the statements they support

Which drugs share a target with Gavestinel, and which of those have an active Phase 3 trial?

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