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AL-034
go.drugbank.com/drugs/DB17471InvestigationalAL-034 (TQ-A3334) is an oral toll-like receptor 7 agonist developed for the treatment of chronic hepatitis B (CHB) viral infection.
Olaflur
go.drugbank.com/drugs/DB13290InvestigationalOlaflur which is also referred to as elmex gel is an ingredient used in toothpaste which helps in the prevention of dental caries.
Mixtures: Nobaton 1% Alpha Hydroxy Acid AmpouleCategories: Compounds used in a research, industrial, or household settingDiridavumab
go.drugbank.com/drugs/DB12607InvestigationalCr6261 is under investigation in clinical trial NCT02016066 (A Study to Assess the Safety, Pharmacokinetics and Immunogenicity of Diridavumab in Japanese Healthy Participants).
4-Methyl-2,5-dimethoxyamphetamine
go.drugbank.com/drugs/DB01528ExperimentalIllicitA psychedelic phenyl isopropylamine derivative, commonly called DOM, whose mood-altering effects and mechanism of action may be similar to those of LSD.
Salts: 2,5-dimethoxy-4-methylamphetamine hydrochloride(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium
go.drugbank.com/drugs/DB02648ExperimentalIt is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. [PubChem]
Synonyms: (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-AmmoniumTMC-310911
go.drugbank.com/drugs/DB15623InvestigationalTMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available [darunavir]. … TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, making it a potentially desirable therapy for
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDesmoteplase
go.drugbank.com/drugs/DB04925InvestigationalDesmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots. … When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting.
Synonyms: rDSPA alpha 1, Salivary plasminogen activator alpha 1, Desmodus rotundusN-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide
go.drugbank.com/drugs/DB06942ExperimentalN-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-l-prolinamide is a solid. This compound belongs to the alpha amino acid amides. These are amide derivatives of alpha amino acids. … This medication targets the protein prothrombin.
Synonyms: N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamidePTI-801
go.drugbank.com/drugs/DB05300InvestigationalPTI-801 represents a new class of drugs to treat pain. PTI-801 can minimize the opioid tolerance, dependence or addiction that is often associated with repeat use of oxycodone. … It is a combination of oxycodone with ultralow-dose naltrexone, an opioid antagonist.
Zastaprazan
go.drugbank.com/drugs/DB21524InvestigationalZastaprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Zastaprazan is a proton pump inhibitor, not dependent on acid activation. … Zastaprazan is under investigation in clinical trial NCT05814809 (Clinical Trial to Evaluate the Safety and Pharmacokinetics of JP-1366 in Healthy Adult Volunteers).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates