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Denileukin diftitox
go.drugbank.com/drugs/DB00004ApprovedInvestigational>387</sub>)-His and the sequence for human interleukin-2 (IL-2; Ala<sub>1</sub>-Thr<sub>133</sub>). … Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub
Synonyms: N-L-METHIONYL-387-L-HISTIDINE-388-L-ALANINE-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE STRAIN C7) (388->2') PROTEIN WITH 2-133-INTERLEUKIN 2 (HUMAN CLONE PTIL2-21A), N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2Sermorelin
go.drugbank.com/drugs/DB00010ApprovedWithdrawnSermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing
Darbepoetin alfa
go.drugbank.com/drugs/DB00012ApprovedInvestigationalHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Products: g/0.5 ml, g/0.5 mlReteplase
go.drugbank.com/drugs/DB00015ApprovedInvestigationalWithdrawnRetavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains the activity-related kringle-2 and serine protease domains of human tPA. … Three domains are deleted from retavase - kringle-1, finger, and epidermal growth factor (EGF).
Synonyms: Human t-PA (residues 1-3 and 176-527)Products: RAPILYSIN 10 U IV ENJ. ICIN STERIL LIYOFILIZE TOZ ICEREN FLAKON, 2 ADETPegfilgrastim
go.drugbank.com/drugs/DB00019ApprovedInvestigationalPegfilgrastim is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (G-CSF) analogue, [filgrastim]. … It is typically administered via a subcutaneous injection.
Synonyms: 吉新芬, PEG-G-CSFCategories: Compounds used in a research, industrial, or household settingSargramostim
go.drugbank.com/drugs/DB00020ApprovedInvestigationalSargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.
Human immunoglobulin G
go.drugbank.com/drugs/DB00028ApprovedInvestigationalIntravenous immunoglobulin (IVIg) is a mixture of IgG1 and other antibodies derived from healthy human plasma via Cohn fractionation.
Synonyms: Human immunoglobulin G, Immunoglobulin G, humanCategories: Immunoglobulin G, Human Immunoglobulin GInsulin human
go.drugbank.com/drugs/DB00030ApprovedInvestigationalNPH insulin is provided as a crystalline suspension of insulin with protamine and zinc, resulting in an onset of action in 1 to 3 hours, duration of action up to 24 hours, and peak action from 6 to 8 hours … Human Insulin, also known as Regular Insulin, is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Mixtures: HUMULIN ® 70/30, HUMULIN ® 70/30Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersInterferon alfa-2a
go.drugbank.com/drugs/DB00034ApprovedInvestigationalWithdrawnInterferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23.
International brands: Roferon ACategories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsPalifermin
go.drugbank.com/drugs/DB00039ApprovedInvestigationalPalifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]
Synonyms: 24-163 fibroblast growth factor 7 (human)