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Displaying results 5801 - 5810 of 10000 in total
  1. Drug

    Navitoclax

    go.drugbank.com/drugs/DB12340
    Investigational

    Navitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of lymphomas and other types of cancer. … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies,

    Synonyms: (R)-4-(3-Morpholin-4-Yl-1-Phenylsulfanylmethyl-Propylamino)-N-(4-{4-[2-(4-Chlorophenyl)-5,5-Dimethylcyclohex-1-Enylmethyl]-Piperazin-1-Yl}-Benzoyl)-3-Trifluoromethanesulfonylbenzenesulfonamide
  2. Drug

    ChulaCov19 mRNA vaccine

    go.drugbank.com/drugs/DB16445
    Experimental

    The next phase of this study is for phase I and II clinical trials (NCT04566276) beginning in January 2021. … The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678].

  3. Drug

    Inarigivir soproxil

    go.drugbank.com/drugs/DB15063
    Investigational

    Inarigivir soproxil is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic

  4. Drug

    VPM1002

    go.drugbank.com/drugs/DB15801
    Investigational

    VPM1002 is a recombinant BCG vaccine candidate expressing listeriolysin and deficient in urease that is generated in the genetic background of BCG Prague as it has a better safety profile than some other … This recombinant BCG, VPM1002, has been created in response and investigated for preventing pulmonary TB in newborns and TB recurrence in adults through post-exposure immunization.

  5. Drug

    Mesenchymal stem cell-derived exosomes

    go.drugbank.com/drugs/DB24445
    Investigational

    Mesenchymal Stem Cell-Derived Exosomes is under investigation in clinical trial NCT07183384 (MSC Exosome Therapy for Post-Preeclampsia Endothelial Dysfunction). … Mesenchymal Stem Cell-Derived Exosomes is a biologic drug.

  6. Drug

    Ralmitaront

    go.drugbank.com/drugs/DB19128
    Investigational

    Ralmitaront is under investigation in clinical trial NCT04512066 (A Trial of the Efficacy and the Safety of RO6889450 (Ralmitaront) vs Placebo in Patients With an Acute Exacerbation of Schizophrenia or

    Synonyms: 1h-pyrazole-3-carboxamide, 5-ethyl-4-methyl-n-(4-(2s)-2-morpholinylphenyl)-, 5-ethyl-4-methyl-n-(4-((2s)-morpholin-2-yl)phenyl)-1h-pyrazole-3-carboxamide
  7. Drug

    Olprinone

    go.drugbank.com/drugs/DB16847
    Investigational

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Monofluorophosphate ion

    go.drugbank.com/drugs/DB02348
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Barbexaclone

    go.drugbank.com/drugs/DB09001
    Experimental

    With this difference in potency in mind, other pharmacokinetic considerations such as dose titration, daily dosing, and optimal plasma concentration can be considered the same as for the equivalent amount … These reports were conducted in a small series of patients in the 1970s and 1980s, and have yet to be confirmed by larger controlled trials.

  10. Drug

    ALMB-0166

    go.drugbank.com/drugs/DB17937
    Investigational

    ALMB-0166 is a umanized connexin 43 (Cx43) monoclonal antibody being investigated for the treatment of acute spinal cord injury. It was granted FDA orphan designation in November 2018.[L47067]