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Displaying results 5801 - 5810 of 10000 in total
  1. Drug

    D2C7 immunotoxin

    go.drugbank.com/drugs/DB17540
    Investigational

    D2C7-IT is under investigation in clinical trial NCT04160494 (D2C7-IT With Atezolizumab for Recurrent Gliomas). … D2C7 immunotoxin (D2C7-IT) is an investigational dual-specific monoclonal antibody targeting EGFRwt and EGFRvIII with a genetically engineered form of the _Pseudomonas exotoxin_, PE38-KDEL.

    Synonyms: D2C7-IT
  2. Drug

    Abarelix

    go.drugbank.com/drugs/DB00106
    ApprovedWithdrawn

    Synthetic decapeptide antagonist to gonadotropin releasing hormone (GnRH). It is marketed by Praecis Pharmaceuticals as Plenaxis. … Praecis announced in June 2006 that it was voluntarily withdrawing the drug from the market.

  3. Drug

    Adavosertib

    go.drugbank.com/drugs/DB11740
    Investigational

    MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.

  4. Drug

    Autologous DNP-conjugated tumour vaccine

    go.drugbank.com/drugs/DB17361
    Investigational

    Autologous DNP-conjugated tumour vaccine, or melanoma vaccine, is an investigational autologous cell vaccine technology for melanoma.[A254806]

  5. Drug

    GC-373

    go.drugbank.com/drugs/DB15797
    Experimental

    The results showed potent inhibition of the target, suggesting that GC-373 holds therapeutic potential for Covid-19[A219036]. … GC-373 has been shown to inhibit the M<sup>pro</sup> target in various coronavirus strains, including feline, mink, and ferret M<sup>pro</sup> [A219041].

    Categories: Experimental Unapproved Treatments for COVID-19
  6. Drug

    N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide

    go.drugbank.com/drugs/DB03456
    Experimental

    These are compounds containing an alpha amino acid (or a derivative thereof) which bears an acyl group at its terminal nitrogen atom. It is known to target cathepsin K. … N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide is a solid. This compound belongs to the n-acyl-alpha amino acids and derivatives.

    Synonyms: N2-[(benzyloxy)carbonyl]-n1-[(3S)-1-cyanopyrrolidin-3-yl]-l-leucinamide
  7. Drug

    Turnip

    go.drugbank.com/drugs/DB10652
    Approved

    Turnip allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic Extract
  8. Drug

    Chickpea

    go.drugbank.com/drugs/DB10662
    Approved

    Chickpea allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic Extract
  9. Drug

    Dill

    go.drugbank.com/drugs/DB10673
    Approved

    Dill allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic Extract
  10. Drug

    INCB3284

    go.drugbank.com/drugs/DB05130
    Experimental

    INCB3284 is a CCR2 antagonist for Inflammation-driven Diseases.