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Displaying results 5801 - 5810 of 10000 in total
  1. Drug

    PF-03049423 FREE BASE

    go.drugbank.com/drugs/DB33809
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring, Phosphodiesterase 5 Inhibitors
  2. Drug

    BMS-986263

    go.drugbank.com/drugs/DB28821
    Investigational

    BMS-986263 is a biologic drug. … BMS-986263 is under investigation in clinical trial NCT04267393 (Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)).

  3. Drug

    RXC008

    go.drugbank.com/drugs/DB33985
    Experimental

    RXC008 is a small molecule drug. RXC008 is under investigation in clinical trial NCT07832435 (A Phase 2, Placebo-Controlled Study of Oral RXC008 for Crohn's Strictures).

  4. Drug

    MOPEVAC-Las

    go.drugbank.com/drugs/DB33987
    Experimental

    MOPEVAC-Las is a biologic drug. … MOPEVAC-Las is under investigation in clinical trial NCT07833436 (A Randomized, Placebo-controlled Trial, to Evaluate the Safety, Immunogenicity and the Optimal Dose of MOPEVAC-Las Vaccine Candidate Against

  5. Drug

    Cetuximab

    go.drugbank.com/drugs/DB00002
    ApprovedInvestigational

    [A227963] EGFR is often mutated in certain types of cancer and serves as a driver of tumorigenesis. … [A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible for regulating epithelial tissue development and homeostasis.

    Products: ERBITUX ® 5 MG/ML, ERBITUX® 5 MG/ML
  6. Drug

    Dornase alfa

    go.drugbank.com/drugs/DB00003
    ApprovedInvestigational

    Dornase alfa is a biosynthetic form of human deoxyribunuclease I (DNase I) enzyme. It is produced in genetically modified Chinese hamster ovary (CHO) cells using recombinant DNA technology. … Dornase alfa cleaves extracellular DNA to 5´-phosphodinucleotide and 5´-phosphooligonucleotide end products without affecting intracellular DNA.

    Synonyms: Deoxyribonuclease (human clone 18-1 protein moiety)Categories: Recombinant Human Deoxyribonuclease 1
  7. Drug

    Denileukin diftitox

    go.drugbank.com/drugs/DB00004
    ApprovedInvestigational

    Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub … approved to treat a human disease in the US.

    Synonyms: N-L-METHIONYL-387-L-HISTIDINE-388-L-ALANINE-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE STRAIN C7) (388->2') PROTEIN WITH 2-133-INTERLEUKIN 2 (HUMAN CLONE PTIL2-21A), N-MET-187-HIS-388-ALA-1-388-TOXIN (CORYNEBACTERIUM DIPHTHERIAE C7) WITH 1-133-INTERLEUKIN 2
  8. Drug

    Sermorelin

    go.drugbank.com/drugs/DB00010
    ApprovedWithdrawn

    Sermorelin acetate is the acetate salt of an amidated synthetic 29-amino acid peptide (GRF 1-29 NH 2 ) that corresponds to the amino-terminal segment of the naturally occurring human growth hormone-releasing

  9. Drug

    Darbepoetin alfa

    go.drugbank.com/drugs/DB00012
    ApprovedInvestigational

    Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.

    Products: g/0.5 ml, g/0.5 ml
  10. Drug

    Goserelin

    go.drugbank.com/drugs/DB00014
    ApprovedInvestigational

    Goserelin is a synthetic hormone. In men, it stops the production of the hormone testosterone, which may stimulate the growth of cancer cells. … When the medication is stopped, hormone levels return to normal.

    Products: ZOLADEX ® 3.6MG, ZOLADEX ® LA 10.8 MG