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Displaying results 5871 - 5880 of 10000 in total
  1. Drug

    Quingestanol

    go.drugbank.com/drugs/DB13685
    Experimental

    Categories: Sex Hormones and Modulators of the Genital System, Cytochrome P-450 Substrates
  2. Drug

    Hydroxyprogesterone

    go.drugbank.com/drugs/DB14570
    Investigational

    Synonyms: 17-Hydroxypregn-4-en-3,20-dione, Pregn-4-ene-3,20-dione-17-olCategories: Sex Hormones and Modulators of the Genital System, Pregnen (4) Derivatives
  3. Drug

    Benzimate

    go.drugbank.com/drugs/DB05170
    Experimental

    The anti-cancer and anti-viral activity of the benzimidazoles was originally investigated by the Proctor & Gamble Company beginning in the 1990's. … Benzimate is the lead compound selected from a series of compounds known as benzimidazoles.

  4. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. … DNA gyrase is an essential enzyme which controls DNA topology and assists in DNA replication, repair, deactivation, and transcription.

    Categories: 4-Quinolones, P-glycoprotein substratesSynonyms: cis-5-Amino-1-cyclopropyl-7-(3,5-dimethyl-1-piperazinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
  5. Drug

    Totrombopag

    go.drugbank.com/drugs/DB05930
    Investigational

    SB-559448 is a small-molecule drug that mimics the activity of thrombopoietin (TPO), a protein factor that promotes growth and production of blood platelets. … This drug is developed by GlaxoSmithKline and used to treat Thrombocytopenia.Thrombocytopenia (decreased platelet count) is a common side effect of many chemotherapies and can lead to uncontrolled bleeding

  6. Drug

    Spermine

    go.drugbank.com/drugs/DB00127
    InvestigationalNutraceutical

    Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure. … Spermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values.

    Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamine
  7. Drug

    Choline C 11

    go.drugbank.com/drugs/DB09277
    Approved

    Choline C 11 is a marker for cellular proliferation as its main molecule is a precursor for the biosynthesis of phospholipids which are essential components of all cell membranes.

    Synonyms: Choline C 11
  8. Drug

    Clinafloxacin

    go.drugbank.com/drugs/DB14025
    Experimental

    Clinafloxacin is a fluoroquinolone antibacterial currently under research. It has been proven to present good antibiotic properties. … However, its approval and release have been halted due to the presence of serious side effects.

    Categories: 4-Quinolones, Cytochrome P-450 CYP1A2 Inhibitors
  9. Drug

    Exbivirumab

    go.drugbank.com/drugs/DB17747
    Experimental

    It is one of the active ingredients in HepeX-B, a drug product containing two human monoclonal antibodies to the hepatitis B virus (HBV) surface antigen.[A259202] … Exbivirumab is an investigational monoclonal antibody.

    Synonyms: Immunoglobulin g, anti-(hepatitis b surface antigen) (human monoclonal 19.79.5 heavy chain), disulfide with human monoclonal 19.79.5 .lambda. chain, dimer
  10. Drug

    Omega-6 fatty acids

    go.drugbank.com/drugs/DB13168
    InvestigationalNutraceutical

    Omega-6 fatty acids are polyunsaturated fatty acids with a final carbon-carbon double bond in the n-6 position, that is, the sixth bond, counting from the methyl end. … Cells involved in the inflammatory response are typically rich in the n-6 fatty acid arachidonic acid, as generally, eicosanoids derived from n-6 PUFA are pro-inflammatory.

    Synonyms: n-6 fatty acids, ω-6 fatty acids