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Palivizumab
go.drugbank.com/drugs/DB00110ApprovedInvestigationalHumanized monoclonal antibody (IgG1k) produced by recombinant DNA technology, directed to an epitope in the A antigenic site of the F protein of respiratory syncytial virus (RSV). … Palivizumab is composed of to heavy chains (50.6 kDa each) and two light chains (27.6 kDa each), contains 1-2% carbohydrate by weight and has a molecular weight of 147.7 kDa +/- 1 kDa (MALDI-TOF)
Categories: Antiinfectives for Systemic UseProducts: Synagis 100mg/ml solution for Injection, SYNAGIS SOLUTION FOR INJECTION 100MG/MLObinutuzumab
go.drugbank.com/drugs/DB08935ApprovedInvestigationalThis chemical modification significantly enhances its affinity for FcγRIII receptors on immune effector cells. … [L54521] Like other drugs in its class, obinutuzumab targets the CD20 antigen expressed on the surface of pre-B and mature B lymphocytes, mediating B-cell lysis.
Products: GAZYVA 1000 MG/ 40 ML CONCENTRATE FOR SOLUTION FOR INFUSION, GAZYVA CONCENTRATE FOR SOLUTION FOR INFUSION 1000MG/40MLMometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Corticosteroids for inhalation use, Drugs for Obstructive Airway DiseasesProducts: MONOVO 1MG/G SALBE, MOMECUTAN SALBE 1 MG/GTerlipressin
go.drugbank.com/drugs/DB02638ApprovedInvestigationalCompared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. … Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor.[A2601] It is a prodrug of [lypressin], or lysine vasopressin.
Products: GLYPRESSIN FOR INJECTION 1 mg/vial, GLYPRESSIN 1mg/8.5ml solution for injectionPentamidine
go.drugbank.com/drugs/DB00738ApprovedInvestigationalAntiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of pneumocystis pneumonia in HIV-infected patients. … It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
Categories: Antibiotics for Pneumocystis PneumoniaProducts: Pentamidine Isetionate for Injection BP, DBL PENTAMIDINE ISETHIONATE FOR INJECTION BP 300 mg/vialCetuximab
go.drugbank.com/drugs/DB00002ApprovedInvestigational[A227973] EGFR is a member of the ErbB family of receptor tyrosine kinases found in both normal and tumour cells; it is responsible for regulating epithelial tissue development and homeostasis. … [A227963] Approved by the FDA in February 2004 under the brand name ERBITUX, cetuximab is used for the treatment of head and neck cancer and metastatic, KRAS wild-type colorectal cancer, and metastatic
Products: ERBITUX 5MG/ML SOLUTION FOR INFUSION, ERBITUX 100 MG/20 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADETMontelukast
go.drugbank.com/drugs/DB00471ApprovedInvestigationalMontelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. … corticosteroids or other agents in asthma step therapy.
Synonyms: (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid, 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acidMixtures: LEVMONT 2.5/4 MG TOZ İÇEREN SAŞE, 90 ADET, EVEREST-DXBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigationalBisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Categories: Drugs for ConstipationProducts: Laxative for Women, Dulcolax for WomenPalonosetron
go.drugbank.com/drugs/DB00377ApprovedInvestigationalits class approved for this use by the U.S. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Solution for Injection 50mcg/ml, ALOXI Solution for Injection 50mcg/mlNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnDue to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries. … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
Categories: Antiinflammatory Preparations, Non-Steroids for Topical Use, Topical Products for Joint and Muscular PainProducts: NI-M-DOL® (NIMESULIDA SUSPENSION), FRENAG FORT %3 JEL, 30 GRAM