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Displaying results 581 - 590 of 10000 in total
  1. Drug

    STM-217

    go.drugbank.com/drugs/DB17358
    Experimental

    Synonyms: Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a
  2. Drug

    Combretastatin A4

    go.drugbank.com/drugs/DB14680
    Experimental

    Synonyms: Combretastatin A-4, 2'-deoxycombretastatin A1
  3. Drug

    Antineoplaston A10

    go.drugbank.com/drugs/DB11702
    Investigational

    Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.

    Synonyms: Antineoplaston A 10, BENZENEACETAMIDE, N-(2,6-DIOXO-3-PIPERIDINYL)-, (S)-Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE

    go.drugbank.com/drugs/DB07072
    Experimental

    Synonyms: (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE
  5. Drug

    Repotrectinib

    go.drugbank.com/drugs/DB16826
    ApprovedInvestigational

    Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the … [A262056] Repotrectinib possesses a compact macrocyclic structure that both limits adverse interactions with resistance mutation hotspots and targets mutations in the solvent-front region.

    Categories: MATE 2 Inhibitors, P-glycoprotein inhibitorsSynonyms: (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN-9-ONE, (7S,13R)-11-Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4(5H)-One
  6. Drug

    (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE

    go.drugbank.com/drugs/DB07717
    Experimental

    Synonyms: (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE
  7. Drug

    Vactosertib

    go.drugbank.com/drugs/DB15310
    Investigational

    Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).

    Synonyms: 2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]anilineCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    PEP0101

    go.drugbank.com/drugs/DB18572
    Experimental

    PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.

    Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.
  9. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  10. Drug

    Ozanezumab

    go.drugbank.com/drugs/DB12891
    Investigational

    Ozanezumab has been used in trials studying the treatment of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis, Relapsing-Remitting.

    Synonyms: IMMUNOGLOBULIN G1, ANTI-(PROTEIN NOGO-A) (HUMAN-MUS MUSCULUS MONOCLONAL HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LIGHT CHAIN, DIMER