Search
V591
go.drugbank.com/drugs/DB16438InvestigationalThrough Merck’s acquisition of Thermis in May 2020, they were able to leverage Thermis’ platform knowledge and accelerate the development of V591 to phase I clinical trials (NCT04498247)[L30593]. … The V591 vaccine, part of Merck’s COVID-19 vaccine programming, was developed using a modified measles vaccine virus as a vector for COVID-19 antigen delivery[L30593].
Idraparinux
go.drugbank.com/drugs/DB06406InvestigationalAs a result, Sanofi stopped the development of the drug. … It was developed for the treatment and prevention of thromboembolic events. However, clinical trials have revealed that idraparinux had lead to bleeding.
Probiorinse
go.drugbank.com/drugs/DB15870Experimental[L16368] This strain of bacteria is said to have salubrious effects on the microbiome of the nasal cavity and sinuses.[A220193] … Probiorinse is an intranasal probiotic treatment composed of a pre-mixed and buffered sinus irrigation solution that contains the probiotic bacteria Lactococcus lactis W136.
CK0802
go.drugbank.com/drugs/DB15866Investigational[L16358] On the surface of these T-Reg cells, T-cell lung homing markers are expressed. … CK0802 is an off-the-shelf product composed of allogeneic umbilical cord blood derived regulatory T-cells (T-Reg cells), which can be used intravenously and without HLA matching.
Synonyms: Allogeneic Umbilical Cord Blood Derived Regulatory T-CellsSynephrine
go.drugbank.com/drugs/DB09203InvestigationalThe similarity of naming between m-synephrine and the unsubstituted form, synephrine, is a source of some confusion however m-synephrine refers to a related drug more commonly known as phenylephrine. … Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid.
Serabelisib
go.drugbank.com/drugs/DB14935InvestigationalSerabelisib is under investigation in clinical trial NCT02625259 (A Study to Evaluate the Relative Bioavailability, Effect of Food, and Gastric Potential Hydrogen (pH) Modification on the Pharmacokinetics
ABT-072
go.drugbank.com/drugs/DB15156InvestigationalABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat
Guanosine-5'-Triphosphate
go.drugbank.com/drugs/DB04137ExperimentalA guanine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Cytidine-5'-Triphosphate
go.drugbank.com/drugs/DB02431ExperimentalA cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalExosomes from MSCs carry cytokines and growth factors, like TGFB1, IL-6, IL-10, and hepatocyte growth factor (HGF); all are shown to be immunomodulatory. … Exosomes are nanometer-sized, membrane-bound vesicles secreted for the purpose of cell-cell communication.