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Displaying results 5931 - 5940 of 10000 in total
  1. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    either 10 or 30μg of BNT162b1, with further improvements following a second dose. … [L15017, L15022] BNT162b1 received fast track designation by the FDA on July 13, 2020.[L15027]

  2. Drug

    Tarenflurbil

    go.drugbank.com/drugs/DB05289
    Investigational

    Aβ42 is the primary initiator of neurotoxicity and amyloid plaque development in the brains of Alzheimer's disease patients. … In June 2008 development of the drug for Alzheimer's disease was discontinued. Tarenflurbil has also been used in trials studying the treatment of Prostate Cancer.

  3. Drug

    SPP 301

    go.drugbank.com/drugs/DB05290
    Investigational

    This study was designed to evaluate whether avosentan influences the pharmacokinetics of steroid oral contraceptives.

  4. Drug

    Veglin

    go.drugbank.com/drugs/DB05890
    Experimental

    VEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma … Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization in the ongoing struggle to combat malignant mesothelioma.

  5. Drug

    Sirna-027

    go.drugbank.com/drugs/DB05896
    Investigational

    VEGFR-1 is a key component of the clinically validated vascular endothelial growth factor (VEGF) pathway. Sirna-027 is developed by Sirna Therapeutics and is under the phase I of clinical trails.

  6. Drug

    Dental Mesenchymal Pulp Stem Cells

    go.drugbank.com/drugs/DB15737
    Investigational

    They are harvested through surgical extraction of wisdom teeth from adults; this procedure is favoured as it is non-invasive, easily accessible, and allows for an alternate use of teeth that are usually … Dental pulp is a soft, connective tissue present in the dental crown of both third molar and first premolar teeth.

  7. Drug

    Guanoxan

    go.drugbank.com/drugs/DB13211
    Approved

    Guanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage.

  8. Drug

    Cinalukast

    go.drugbank.com/drugs/DB00587
    Experimental

    Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. … Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway.

  9. Drug

    Actinium Ac 225 Vipivotide tetraxetan

    go.drugbank.com/drugs/DB23637
    Investigational

    for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma). … Actinium Ac 225 Vipivotide Tetraxetan is under investigation in clinical trial NCT07150715 (Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy

  10. Drug

    Proxalutamide

    go.drugbank.com/drugs/DB16065
    Investigational

    Proxalutamide is under investigation in clinical trial NCT03899467 (The Safety and Tolerability of Proxalutamide (GT0918) in Subjects With Metastatic Castrate Resistant Prostate Cancer).