Search
Zunsemetinib
go.drugbank.com/drugs/DB16502InvestigationalATI-450 was under investigation in clinical trials (NCT05279417 and NCT05216224) for treating patients with rheumatoid arthritis and hidradenitis suppurativa, respectively. Additionally, ATI-450 was studied in a terminated trial (NCT0551...
5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole
go.drugbank.com/drugs/DB08722ExperimentalThese are aromatic compounds containing an ether group substituted with a benzene ring. 5-(7-(6-chloro-4-(5-hydro-4-methyl-2-oxazolyl)phenoxy)heptyl)-3-methyl isoxazole targets the protein genome polyprotein
Deanol
go.drugbank.com/drugs/DB13352InvestigationalIt has been also used as an ingredient in skin care, and in cognitive function- and mood-enhancing products.
RUTI® Vaccine
go.drugbank.com/drugs/DB15853InvestigationalSponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488).
Cyclin-dependent kinases
go.drugbank.com/bio_entities/BE0010231TargetHumansCan phosphorylate CCNY at 'Ser-336' (in vitro) … The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro (PubMed:21127351).
Synonyms: CAK, CAK-kinase p42KOS-2187
go.drugbank.com/drugs/DB05946ExperimentalKOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease (GERD).
DDP-225
go.drugbank.com/drugs/DB05642InvestigationalDDP225 is both a noradrenaline reuptake inhibitor and a serotonin type 3 receptor (5-HT3) antagonist. Noradrenaline and serotonin are neurotransmitters that are known to be involved in the control of the gastrointestinal system. The uniq...