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Nurulimab
go.drugbank.com/drugs/DB18946InvestigationalNurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in
CDX-1135
go.drugbank.com/drugs/DB17607InvestigationalCDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex). … It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage.
Dexpemedolac
go.drugbank.com/drugs/DB19987ExperimentalDexpemedolac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Dexpemedolac is a anti-inflammatory agent, ibufenac derivative. … Dexpemedolac has a monoisotopic molecular weight of 349.17 Da.
Isofezolac
go.drugbank.com/drugs/DB20228ExperimentalIsofezolac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Isofezolac is a anti-inflammatory agent, ibufenac derivative. … Isofezolac has a monoisotopic molecular weight of 354.14 Da.
Clopirac
go.drugbank.com/drugs/DB20824ExperimentalClopirac is a small molecule drug. The usage of the INN stem '-ac' in the name indicates that Clopirac is a anti-inflammatory agent, ibufenac derivative. … Clopirac has a monoisotopic molecular weight of 263.07 Da.
FP0011
go.drugbank.com/drugs/DB05090ExperimentalFP0011 is a small molecule antiglutamatergic compound with symptomatic and disease modifying effects in a variety of neurological disorders (amyotrophic lateral sclerosis and Parkinson's disease). … It acts on the presynaptic regulation of glutamate and shows strong neuroprotective properties.
RAV12
go.drugbank.com/drugs/DB05140InvestigationalRAV12 is a solid. RAV12 is a chimeric antibody that recognizes RAAG12, an N-linked carbohydrate antigen found on gastric, colon, pancreatic, prostate, ovarian, breast, and kidney cancer cells.
Human Embryonic Stem Cell-derived M Cell
go.drugbank.com/drugs/DB15734InvestigationalCAStem is composed of immunity- and matrix-regulatory cells (IMRCs), also known as M cells, which can be administered through injection. … However, the difference comes with IMRCs displaying a higher quality of consistency, having stronger immunomodulatory and anti-fibrotic functions, and being stronger in potential treatment of lung injury
EP-1043
go.drugbank.com/drugs/DB06118ExperimentalEP-1043 is an epitope-based recombinant protein vaccine designed to induce HIV-1 specific helper T-lymphocyte (HTL) responses. … The vaccine consists of a string of 18 HIV-derived major histocompatibility complex (MHC) Class II restricted epitopes, each separated by a spacer designed to optimize potency.
Ulimorelin
go.drugbank.com/drugs/DB12128InvestigationalUlimorelin is a novel small molecule ghrelin agonist being developed by Tranzyme Pharma as a first-in-class treatment for both POI and diabetic gastroparesis, serious medical conditions in which motility