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Forodesine
go.drugbank.com/drugs/DB06185InvestigationalForodesine is a highly potent, orally active, rationally designed PNP inhibitor that has shown activity in preclinical studies with malignant cells and clinical utility against T-cell acute lymphoblastic
CX-717
go.drugbank.com/drugs/DB05047IllicitInvestigationalCX-717 is an ampakine compound previously investigated for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and Alzheimer's disease.
Plazinemdor
go.drugbank.com/drugs/DB21493InvestigationalPlazinemdor is under investigation in clinical trial NCT04306146 (Study of CAD-9303 in Subjects With Schizophrenia). Plazinemdor has a monoisotopic molecular weight of 432.12 Da.
Brivoligide
go.drugbank.com/drugs/DB16116InvestigationalBrivoligide is under investigation in clinical trial NCT04104919 (Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Mastectomy in Patients With High PCS Scores).
Isoquercetin
go.drugbank.com/drugs/DB12665InvestigationalIsoquercetin has been used in trials studying the treatment of Kidney Cancer, Renal cell carcinoma, Advanced Renal Cell Carcinoma, Thromboembolism of Vein in Pancreatic Cancer, and Thromboembolism of Vein … VTE in Colorectal Cancer, among others.
Edivoxetine
go.drugbank.com/drugs/DB09184InvestigationalEdivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant … Edivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012.
Amcipatricin
go.drugbank.com/drugs/DB12333InvestigationalAmcipatricin has been used in trials studying the treatment of Cryptococcosis or Aspergillosis Infections. … In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp.
Oditrasertib
go.drugbank.com/drugs/DB21526InvestigationalOditrasertib has a monoisotopic molecular weight of 295.11 Da. … Oditrasertib is under investigation in clinical trial NCT05630547 (A Study to Evaluate the Effect of SAR443820 on Serum Neurofilament Levels in Male and Female Adult Participants With Multiple Sclerosis