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Afamitresgene autoleucel
go.drugbank.com/drugs/DB18592ApprovedInvestigational[L51114] The transduced T cells are expanded, washed, formulated into a suspension, and cryopreserved. … [L51114] MAGE-A4 is an intracellular cancer-testis antigen that is overexpressed by cancer cells in synovial sarcoma.
Synonyms: AUTOLOGOUS CD4+ AND CD8+ T CELLS OBTAINED BY LEUKAPHERESIS, TRANSDUCED WITH AN HIV-DERIVED SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR, ENCODING AN ENHANCED-AFFINITY T CELL RECEPTOR (TCR) SPECIFIC FOR THERomilkimab
go.drugbank.com/drugs/DB16318InvestigationalRomilkimab is under investigation in clinical trial NCT02345070 (Efficacy and Safety of SAR156597 in the Treatment of Idiopathic Pulmonary Fibrosis).
Synonyms: Bispecific antibody targeting interleukin 4 (IL-4) and interleukin 13 (IL-13)Radotermin
go.drugbank.com/drugs/DB19127InvestigationalRadotermin is under investigation in clinical trial NCT01182337 (A Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of Single Administration Intradiscal Rhgdf-5 for the
Synonyms: Recombinant human growth and differentiation factor-5Mucor circinelloides f. circinelloides
go.drugbank.com/drugs/DB15512ApprovedMucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Synonyms: Molds, rusts and smuts, mucor circinelloides f. circinelloidesMentha arvensis top
go.drugbank.com/drugs/DB14346InvestigationalMentha arvensis top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Synonyms: Mentha Herb, Mentha arvensis topFactor IX Complex (Human)
go.drugbank.com/drugs/DB11330ApprovedInvestigationalCoagulation factors are purified from pooled human plasma and subsequently sterilized and treated. … For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) contains heparin.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsSynonyms: Coagulation factor IX, II, VII and X in combinationFluorescein
go.drugbank.com/drugs/DB00693ApprovedInvestigationalinjuries and corneal trauma. … A phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal
Synonyms: D and C Yellow No. 7Mixtures: Minims Lidocaine and Fluorescein, Fluorescein Sodium and Proparacaine HydrochlorideNogapendekin alfa
go.drugbank.com/drugs/DB18740ApprovedInvestigational[A263617, A263622] Nogapendekin alfa, in combination with inbakicept, mimics the actions of IL-15, , stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which … [L50627] Non-muscle invasive bladder cancer (NMIBC), which accounts for 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and Bacillus Calmette-Guérin (
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsSynonyms: Fusion protein consisting of il-15n72d and il-15rasu/fcGoflikicept
go.drugbank.com/drugs/DB16396InvestigationalGoflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory proteinCHF5633
go.drugbank.com/drugs/DB18696InvestigationalCHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a
Categories: Amino Acids, Peptides, and ProteinsSynonyms: Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue